Spinal Cord Injuries Clinical Trial
Official title:
Activity-Dependent Plasticity After Spinal Cord Injury
Incomplete spinal cord injury often results in difficulty walking. Training on a treadmill with body weight support may improve walking ability after spinal cord injury. The purpose of this study is to examine the effect of treadmill speed on spinal cord function and walking performance.
Status | Active, not recruiting |
Enrollment | 16 |
Est. completion date | January 2005 |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 6 Years to 65 Years |
Eligibility |
Inclusion criteria: - First time spinal cord injury (SCI) from trauma, vascular, or orthopedic pathology at cervical or thoracic levels - Category C or D SCI as defined by the American Spinal Injury Association (ASIA) Impairment Scale - 1 to 3 years post-SCI - Ability to walk independently a minimum of 40 feet with or without an assistive device - Currently spending a minimum of 30 minutes per day walking - No change in anti-spasticity medication during the study - Medically stable - Participant's personal physician must verify the participant's medical status Exclusion criteria: - Bladder infection, decubiti, osteoporosis, cardiopulmonary disease, pain, or other significant medical complications that would prohibit or interfere with training and testing of walking function or alter compliance with a training protocol - Currently participating in a rehabilitation program or another research protocol that could interfere or influence the outcome measures of the current study - Congenital SCI (e.g., Chiari malformation, myelomeningocele, intraspinal neoplasm, Frederich's ataxia) - Other degenerative spinal disorders (e.g., spinocerebellar degeneration, syringomyelia) that may complicate the treatment or evaluation procedures |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
United States | University of Florida | Gainesville | Florida |
Lead Sponsor | Collaborator |
---|---|
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | VA Office of Research and Development |
United States,
Barbeau H, Norman K, Fung J, Visintin M, Ladouceur M. Does neurorehabilitation play a role in the recovery of walking in neurological populations? Ann N Y Acad Sci. 1998 Nov 16;860:377-92. Review. — View Citation
Behrman AL, Harkema SJ. Locomotor training after human spinal cord injury: a series of case studies. Phys Ther. 2000 Jul;80(7):688-700. Review. — View Citation
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