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Spasticity clinical trials

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NCT ID: NCT02291159 Completed - Stroke Clinical Trials

Effects of DNHS Technique in the Treatment of Upper Limb Spasticity and Function in Stroke

Start date: November 2014
Phase: N/A
Study type: Interventional

Introduction: Stroke is a neurological deficit caused by a decrease in cerebral blood flow. The DNHS ® (Dry Needling for hypertonia and Spasticity) technique is a dry needling technique to reduce spasticity and hypertonia and improve function in patients with CNS injury. The main objective of this trial is to analyze the therapeutic effect of DNHS® technique in motor function in patients between 45 and 80 in a chronic state after a stroke. Methods: Double-blinded randomized clinical trial. There will be an intervention group (DNHS® technique) and a sham control group. The intervention will be 2 sessions, one per week, in biceps brachii, brachialis, flexor digitorum superficialis nad profundus, adductor pollicis and first dorsal interossei. The Fugl Meyer Assessment Scale, Modified Ashworth Scale and Stroke Impact Scale will be used as outcome measures. The data will be expressed as mean ± (Standard Deviation). The standardized difference or effect size (ES, 90% confidence limit) in the selected variables will be calculated.

NCT ID: NCT02275312 Completed - Spasticity Clinical Trials

ETREAT Study on Effectiveness of Botulinum Toxin Type A Injections to Treat Post-stroke Upper and/or Lower Limb Spasticity

ETREAT
Start date: July 2014
Phase:
Study type: Observational

The objective of this study is to evaluate the effectiveness of BoNT-A on functional improvement in patients with post-stroke upper and/or lower limb spasticity in the early stage of spasticity development, according to routine clinical practice.

NCT ID: NCT02268461 Completed - Spasticity Clinical Trials

Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment of Post-Stroke Spasticity

Start date: December 2014
Phase: N/A
Study type: Interventional

Spasticity is a common complication of stroke affecting quality of life. Spasticity involves exaggerated stretch reflexes that create stiffness in muscles with associated loss of motion and functional control. Traditional treatments involve range of motion, medications, and sometimes surgery. Each of these has its own limitations, which has invited exploration of alternative modes of treatment. One such treatment with the potential to benefit spasticity is repetitive Transcranial Magnetic Stimulation (rTMS). The purpose of this study is to determine whether patients with upper limb spasticity as a consequence of a chronic stroke can benefit from stimulation of the non-affected hemisphere of the brain with low-frequency (inhibitory) repetitive Transcranial Magnetic Stimulation (rTMS), potentially leading to a reduction of spasticity and clinical improvement in upper limb function.

NCT ID: NCT02261142 Completed - Stroke Clinical Trials

Efficacy and Cost-effectiveness of Spasticity Treatment With Multifocal TENS

Start date: September 2013
Phase: N/A
Study type: Interventional

Spasticity is a common consequence of injury to the central nervous system and can be a major problem in motor function and everyday activities. A method for treating spasticity that applies low-amplitude electrical stimulation through a garment with built-in electrodes, Mollii® (Elektrodress), has been developed. The garment is to be used in combination with individualized training and the stimulation is mainly given to antagonists of spastic muscles. The general objective of this study is to evaluate the efficacy of and costs associated with the Mollii® treatment of spasticity due to stroke or cerebral palsy. Primary objectives are; - to study whether treatment with the Mollii® improves function and activity - to evaluate the cost-effectiveness of the treatment, from both a health-care perspective and a societal perspective. Secondary objectives are; - to study whether there are differences in treatment effect between the stroke and the Cerebral Palsy groups in a subgroup-analysis - to assess compliance with treatment - to report any adverse effects.

NCT ID: NCT02228863 Recruiting - Stroke Clinical Trials

Upper Extremity Rehabilitation Using Robot and Botulinum Toxin

Start date: March 2014
Phase: Phase 4
Study type: Interventional

Concomitant use of botulinum toxin and robot would make better results regarding upper extremity function compared to robot, botulinum toxin, or no intervention.

NCT ID: NCT02221011 Completed - Spasticity Clinical Trials

The Effect of Extracorporeal Shock Wave Therapy on Spasticity

Start date: August 2014
Phase: N/A
Study type: Interventional

The effect of traditional treatment for spasticity is barely satisfactory. The shock wave has been used to treat the spasticity with expressively response and the effect could persist for 1-3 months in different studies. However most sutdies lack the sham or control group. The purpose of this study was to assess the effect of shock wave for spasticity in wrist and hand.

NCT ID: NCT02203994 Completed - Spinal Cord Injury Clinical Trials

Extracorporeal Shock Wave Therapy (ESWT) for the Treatment of Spasticity in Persons With Spinal Cord Injury

ESWT
Start date: July 2014
Phase: N/A
Study type: Interventional

Spasticity is the most problematic self-reported secondary medical problem in patients with spinal cord injury. It has the potential to negatively influence quality of life through restricting activities of daily living. Problematic spasticity can cause pain and fatigue, disturb sleep, contribute to the developement of contractures and pressure ulcers, and has a negative effect on patients morbidity. For this reason there is enormous interest in therapeutic interventions addressing to decrease spasticity in persons with spinal cord injury. Recently, studies reported positive effects of extracorporeal shock wave therapy on spasticity in patients with stroke, focal limb dystonia and cerebral palsy. To date, no studies are published, assessing the effect of extracorporeal shock wave therapy on focal spasticity in patients with spinal cord injury. The purpose of this study is to investigate the effect of a one-time ESWT on lower limb spasticity in patients with an incomplete spinal cord injury.

NCT ID: NCT02199015 Not yet recruiting - Cerebral Palsy Clinical Trials

Lateral Cord Stimulation as a New Treatment for Refractory Spastic Cerebral Palsy

Andreani1
Start date: June 1, 2025
Phase: N/A
Study type: Interventional

The aim of our work is to investigate whether electrical Lateral Cord Stimulation (LCS) causes an inhibitory and modulatory action by indirect cerebellar activation, so releasing spasticity and the spastic syndrome in selected cases of patients with cerebral palsy

NCT ID: NCT02170779 Completed - Multiple Sclerosis Clinical Trials

Developing and Testing a Comprehensive MS Spasticity Management Program

Start date: October 2015
Phase: Phase 2
Study type: Interventional

This is a study to determine the impact of education and specific lower extremity stretches for MS-related spasticity. The study will evaluate the acceptance and efficacy of education and stretching using a randomized controlled pilot trial.

NCT ID: NCT02127606 Recruiting - Spinal Cord Injury Clinical Trials

The Effect of Whole Body Vibration on Spasticity in Persons With Spinal Cord Injury

Start date: April 2014
Phase: N/A
Study type: Interventional

Extended periods of tilt table standing have been observed to improve spasticity in individuals with spinal cord injury (SCI). The purpose of this study is to determine the effect of three sessions of whole body vibration while tilt table standing on spasticity in individuals with a complete or incomplete SCI above the neurological level of T10. Participants in this study will undergo whole body vibration while standing on a tilt table for a total of approximately 14 minutes for a total of 3 sessions on 3 separate days. Spasticity monitoring will be evaluated prior to and after the intervention with the Modified Penn Spasm Frequency Scale, an interview to obtain the individual's perception and impression of the effect of whole body vibration on the performance of activities of daily living, quality of life, pain scale, and global impression of change.