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Clinical Trial Summary

This is a pilot, experimental, monocentric study. The main objective of the study is to evaluate whether stereotactic radiotherapy is able to reduce symptomatic spasticity from a clinical point of view, and therefore induce an improvement in posture and quality of life in patients with malignant spasticity. The study foresees the enrollment of about 10 patients, in a period of 24 months. The radiotherapy treatment will be delivered in a single session with an image-guided stereotaxic technique, and a prescription dose between 45 and 60 Gy; subsequently the patients will be followed up for one year.


Clinical Trial Description

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Study Design


Related Conditions & MeSH terms


NCT number NCT06309810
Study type Interventional
Source IRCCS Sacro Cuore Don Calabria di Negrar
Contact Elvia Malo
Phone +390456014854
Email ricerca.clinica@sacrocuore.it
Status Recruiting
Phase N/A
Start date March 6, 2023
Completion date August 2025