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Social Isolation clinical trials

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NCT ID: NCT06335836 Recruiting - Alzheimer Disease Clinical Trials

The Effects of Social Isolation and Social Interaction on the Risk of Dementia Progression and Brain Function in SCD (Subjective Cognitive Decline, SCD)

Start date: March 1, 2024
Phase:
Study type: Observational [Patient Registry]

The goal of this clinical trial is to learn about the effects of social isolation and social interaction on the risk of dementia progression and brain function in SCD 1. To explore the association between social isolation and lonely SCD populations and the occurrence and progression of MCI and AD through cross-sectional studies, cohort studies and randomized controlled trials of SCD; 2. To clarify the correlation between different carrier states, resting brain function connectivity characteristics, and dual-task walking ability of APOEε4 allele and the progression of SCD to MCI and AD during the cognitive progress of people with SCD affected by social isolation; 3. Establish a predictive model of cognitive decline from SCD to MCI and AD, and apply it to the SCD population to carry out individualized interventions; 4. Confirm the protective effect of social interaction on cognitive level and brain function in SCD patients.

NCT ID: NCT06175299 Recruiting - Social Isolation Clinical Trials

Social Functions to Promote Home-based Cognitive Training

DeepCare
Start date: September 30, 2023
Phase: N/A
Study type: Interventional

This study will examine whether among older adults social interaction functions in a home-based cognitive training program can better support adherence to training and reduce social isolation.

NCT ID: NCT06138301 Recruiting - Social Isolation Clinical Trials

Telepsychiatry for Social Isolation in Youths

SOLITAIRE
Start date: September 1, 2023
Phase: N/A
Study type: Interventional

This clinical trial aims to implement multimodal digital interventions for adolescents and young adults with social isolation (SI) and their family members. Furthermore, the neurobiological basis of SI will be explored by analyzing blood neuroinflammation biomarkers in socially isolated participants. The main questions that this project aims to answer are: - What is the general feasibility and applicability of the proposed digital interventions? - What is the effect of the proposed digital interventions on the SI-related clinical symptoms and the cognitive and global functioning of participants with SI? Participants will be asked to undergo: - A detailed clinical and neuropsychological evaluation (pre-post treatment) - A blood sample (pre-post treatment) - A telepsychiatry intervention (cognitive behavioural therapy (CBT) and/or cognitive remediation (CR) for SI participants and psychoeducation (PE) for family members) The researchers will compare SI participants treated with CBT+CR (experimental group) with SI patients treated only with CBT (control group) to see if the combined intervention of the experimental group leads to more durable and generalizable effects. The same PE intervention will be offered to the family members of all recruited SI participants.

NCT ID: NCT05998343 Recruiting - Loneliness Clinical Trials

Intergenerational Program for Social Isolation and Loneliness in Older Adults Discharged From the Emergency Department

SIL
Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Social isolation and loneliness worsens older adults' risk of dementia, quality of life, and death as much as smoking. Older adults are more likely to use emergency services and are also more likely to experience social isolation and loneliness than younger people. The emergency department is a new setting to screen for social isolation and loneliness in older adults and help accordingly. Social isolation and loneliness are experienced differently by different older adults. Different interventions combatting social isolation and loneliness may work better for different people, and little is known about older adult's preferences for specific types of interventions. HOW R U? is an effective and feasible intervention using same-generation peer support offered by trained hospital volunteers to reduce social isolation and loneliness in older adults. In partnership with the Australian developer of HOW R U?, this study will compare an intergenerational HOW R U? intervention using younger volunteers with the same-generation peer support intervention and a waitlist control arm. The investigators partnered with the staff of emergency departments and family medicine clinics to identify people who will benefit from an intervention combatting, and Volunteer Services to recruit volunteers. The investigators hypothesize that the older adults who receive the intergenerational HOW R U? intervention will have a greater improvement in social isolation and loneliness.

NCT ID: NCT05978934 Recruiting - Physical Activity Clinical Trials

Determining How Indoor Lighting Affects the Brain Health of Older Adults

Start date: May 15, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized, cross-over, single-site trial followed by an exploratory third intervention is to understand how indoor lighting affects different measures of brain health in older adults living in independent living residences. This is a community based study occurring in a local senior living facility. The main question this study aims to answer is: - How does the quality of ambient indoor lighting an older adult is exposed to affect measures of brain health, such as sleep quality, physical activity, cognitive function, and social engagement? Participants will be exposed to three different indoor lighting conditions for 4 weeks each while performing the following tasks: - Wear a smartwatch throughout the study to measure sleep quality and physical activity - Wear a small, wearable light sensor to measure light exposure during waking hours - Perform cognitive assessments throughout the study to detect any changes between each of the lighting conditions - Complete self-report of surveys to assess independence, social engagement, sleep quality, and mood Results from these tasks will be compared within and between subjects to assess whether the different lighting conditions affect these different measures of brain health.

NCT ID: NCT05977608 Recruiting - Mental Health Clinical Trials

The Impact of a Telephone Reminiscence Program

Start date: June 25, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to better understand how a telephone reminiscence program impacts reminiscence functions and mental health outcomes in community-dwelling older adults.This study will take 12 weeks to complete and will include approximately 90 study participants. Participants will be randomly assigned to one of two telephone reminiscence groups.They will be either assigned to begin a telephone reminiscence program immediately or in 6 weeks. Participants will receive automatic calls three times a week asking the meaningful questions about their lives. At week 1, week 6, and week 12, participants will also be asked to complete assessments via phone, by research assistants using four questionnaires.

NCT ID: NCT05831475 Recruiting - Loneliness Clinical Trials

LEAPTogether: An Intergenerational Intervention to Address Loneliness and Social Isolation

LEAPTogether
Start date: September 7, 2023
Phase: N/A
Study type: Interventional

Older adult participants will engage in exercise videos twice a week for 8 weeks either while paired with a peer (same age group) or paired with a younger adult with the ability to simultaneously video chat while exercising.

NCT ID: NCT05745493 Recruiting - Quality of Life Clinical Trials

Study 1: Social Engage Coaching R61 Phase

R61 Phase
Start date: June 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to test whether an individual coaching program called Social Engage Coaching (or 'Engage Coaching' for short) helps adults age 60 and older feel more connected to other people in ways that matter to them. Procedures include participating in a Social Engage Coaching program, research assessments with surveys, and assessments completed on a cell phone. Engage Coaching involves individual sessions with a trained Engage Coach (up to 10 sessions) that are designed to help participants improve social relationships and well-being. All subjects will receive the scheduled baseline and follow-up interviews by the research team. These interviews will be conducted at study start, mid-way through the program at 8 weeks and after completing the program at 16 weeks. Interviews will be via Zoom/phone as well as surveys done online.

NCT ID: NCT05520450 Recruiting - Loneliness Clinical Trials

Telematic Support Group in Patients With Feelings of Loneliness and Social Isolation

Start date: September 1, 2022
Phase:
Study type: Observational

Loneliness can have negative consequences, both physically and psychologically. The aim of this study is to evaluate the effects of a telematic group intervention in reducing feelings of loneliness and social isolation, as well as improving the emotional well-being of people in home care. The sample is made up of patients aged 60 to 99 years resident in Sabadell health area who receive regular home care in the ATDOM Programme by the Primary Care Team of the Corporació Sanitària Parc Taulí, who agree to participate in the study and meet the eligibility criteria. The study includes clinical assessments, emotional well-being, social support and satisfaction with the intervention.

NCT ID: NCT05426837 Recruiting - Loneliness Clinical Trials

Combatting Social Isolation in Older Adults

CSI
Start date: July 30, 2022
Phase: N/A
Study type: Interventional

Increasing evidence suggests that perceived social isolation and loneliness are major risk factors for physical and mental illness in later life. The prevalence of loneliness in US older adults warrants concern, with an estimated 30% of American adults aged 70 years and older reporting heightened loneliness. A wide variety of interventions have been developed to address social isolation and loneliness ranging from social facilitation to animal therapies. While many intervention studies have attempted to address loneliness, social isolation and related constructs in older adults, this literature is underdeveloped and there is not an established or widely accepted set of treatments. Moreover, existing treatments tend to be lengthy, burdensome, and result in high dropout rates. Brief, mechanism focused interventions are an alternative to more traditional forms of treatment. Because they are structured and brief, these treatments can be readily placed on the internet, making them extremely efficient, destigmatizing, and highly scalable. The investigators have developed and tested a web-based intervention called "Combating Social Isolation" (CSI) that the investigators believe offers an alternative to existing interventions for loneliness and social isolation in older adults. CSI evolved out of Interpersonal Theories of mood psychopathology (Joiner, 2005) and targets two risk factors central to social disconnection: perceived burdensomeness and thwarted belongingness (PB/TB). The investigators have one randomized clinical trial using CSI and are nearing completion of two other RCTs using this intervention. Evidence shows that CSI has very high levels of acceptability, and despite the brevity of the protocol (approximately 1 hour) can markedly impact loneliness. Moreover, reductions in these risk factors mediate later improvements in mental health outcomes and social disruption. The purpose of the current proposal is to adapt our existing protocol for older adults reporting loneliness and then obtain preliminary acceptability and efficacy data from a Phase II randomized clinical trial.