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Clinical Trial Summary

This study will recruit 460 participants who self-report high symptoms of anxiety. Participants will be randomly assigned to one of 4 groups: one analog intervention of Imagery Rescripting (IR) for memories, an analog intervention of IR for future events, and analog intervention of Imaginal Exposure (IE) for memories and an analog intervention of IE for future events. We will examine the efficacy and mechanisms behind each intervention.


Clinical Trial Description

After being informed about the study potential risks, all patients giving written informed consent will undergo screening to determine eligibility for study entry. They will be randomly assigned to one of four conditions (Imagery rescripting past; Imagery rescripting future; Imaginal exposure past; Imaginal exposure future) at a 1:1:1:1 ratio (n = 115 per group). Participant will be assigned using a variance minimization method that controls for between group variance in continuous and categorical variables- SPIN, ASI-3, OCI-R, GAD-7 and gender with a completely random assignment p random = .2 (for algorithm see Sella et al., 2018). Participants will attend three ~1.5 hour online ZOOM sessions (baseline-assessment and measurement, intervention, post assessment and measurement and follow-up measurement). In this multiple baseline study, participant will enter the intervention phase either 7 or 14 days after the baseline stage. Assessors will be blind to the treatment condition. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05292807
Study type Interventional
Source Hebrew University of Jerusalem
Contact Snir Barzilay, PhD. student
Phone +972 50 4499 435
Email snir.barzilay@mail.huji.ac.il
Status Recruiting
Phase N/A
Start date April 14, 2022
Completion date January 2025

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