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Sleep Apnea, Obstructive clinical trials

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NCT ID: NCT03788668 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea

Role of Hyoid Suspension With Barbed Reposition Pharyngoplasty in Management of Lateral Pharyngeal Wall Collapse in Obstructive Sleep Apnea Patients

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

Aim of the study To determine the exact role of hyoid bone suspension surgery in splinting lateral pharyngeal wall in the era of the lateral pharyngoplasty

NCT ID: NCT03782844 Completed - Clinical trials for Sleep Apnea, Obstructive

Efficacy of Simple Continuous Positive Airway Pressure on Patients With Obstructive Sleep Apnea

Start date: January 2, 2019
Phase: N/A
Study type: Interventional

Obstructive sleep apnea (OSA) is a common and frequently-occurring disease. The incidence of OSA is more than 4% in general population, and as high as 20% - 40% in the elderly. At present, CPAP machines commonly used for OSA treatment includes traditional pressure fixed single-level CPAP machine and automatic pressure regulation CPAP machine. Studies have shown that the CPAP treatment pressure of OSA patients is normally below 11 cmH2O. Since the condition of OSA patients and the required CPAP treatment pressure may change over time, a CPAP machine with automatic pressure regulation function may theoretically better meet the needs of treatment. However, a recent large-scale clinical study with an average follow-up of four years showed that there was little need to change CPAP treatment pressure after titration. Although different types of CPAP have different functions, the basic principle is to keep the upper airway open and unobstructed to eliminate sleep apnea and hypopnea by continuously applying positive pressure to the upper respiratory tract through an air pump. A complex CPAP machine with functions such as pressure regulation, boost delay, end-expiratory pressure release will cost more than a single-function CPAP machine. Some patients from poor areas, even with severe OSA, may give up treatment when they can not afford CPAP machines that have not yet been included in national health insurance in China. In view of the current economic level in China, it is urgent to find an inexpensive and effective CPAP machine for the treatment of OSA and related complications. Recently, Guangzhou Yinghui Medical Technology Co., Ltd.and State Key Laboratory of Respiratory Disease have developed a new simple CPAP machine. The CPAP treatment pressure is fixed at the factory to 6 cm H2O (SKL), 8 cm H2O (SKM) and 10 cm H2O (SKH). Compared to traditional CPAP machine, only a power switch button is attached on the body, and the additional adjustment devices including display screen are removed, which not only reduces the cost of the CPAP machine, but also facilitates the operation of patients.

NCT ID: NCT03777202 Completed - Clinical trials for Obstructive Sleep Apnea

Efficacy of High Flow Nasal Oxygen During Sleep Endoscopy in Patients of Obstructive Sleep Apnea

Start date: July 17, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the utility of high-flow nasal oxygen during sleep endoscopy in obstructive sleep apnea patients.

NCT ID: NCT03776084 Recruiting - Clinical trials for Sleep Apnea, Obstructive

Compliance With Continuous Positive Airway Pressure Therapy in Patients With Obstructive Sleep Apnea Syndrome

CPAPSH
Start date: June 1, 2019
Phase:
Study type: Observational

The aim of the study is to know the adherence to treatment and compliance of patients diagnosed with SAHS and with indication of CPAP from the sleep unit of the Hospital de Sabadell.

NCT ID: NCT03771469 Active, not recruiting - Clinical trials for Obstructive Sleep Apnea

Validation of Sleep Questionnaires in the Down Syndrome Population

Start date: June 25, 2018
Phase: N/A
Study type: Interventional

This will be a prospective validation study of a sample of consecutive pediatric Down syndrome patients who are seen through the weekly Down syndrome clinic at OHSU/Doernbecher's. Questionnaires will be administered to approximately 5 new patients per month. Since this population has a higher prevalence of OSA than the general pediatric population, and OSA is a potentially modifiable determinant of quality of life, validated instruments are critical in assessing disease burden and response to treatment.

NCT ID: NCT03766464 Completed - Clinical trials for Temporomandibular Joint Disorders

Aspects Associated With Obstructive Sleep Apnea, Bruxism and Orofacial Pain

Start date: January 1, 2019
Phase:
Study type: Observational

This study evaluated the influence of the sleep bruxism (SB), awake bruxism (AB) and obstructive sleep apnea syndrome (OSAS) on the signs and symptoms of temporomandibular disorders (TMD).

NCT ID: NCT03765294 Completed - Clinical trials for Obstructive Sleep Apnea

A Study to Investigate the Effects of ACT-541468 on Nighttime Respiratory Function in Patients With Mild to Moderate Obstructive Sleep Apnea

Start date: March 14, 2019
Phase: Phase 1
Study type: Interventional

This study is conducted to investigate the effects of ACT-541468 on nighttime respiratory function in patients with mild to moderate obstructive sleep apnea

NCT ID: NCT03763682 Active, not recruiting - Clinical trials for Obstructive Sleep Apnea

BilatEral Hypoglossal Nerve StimulaTion for TreatmEnt of ObstRuctive SLEEP Apnoea With and Without Complete Concentric Collapse

BETTER SLEEP
Start date: January 10, 2019
Phase: N/A
Study type: Interventional

The objective of this study is to explore the safety and performance of the Genioâ„¢ system in adult obstructive sleep apnoea (OSA) patients with and without complete concentric collapse of the soft palate over a period of 4.5 months of treatment (i.e. 6 months post-surgery) measured by the AHI, at rest to determine if there is a difference in performance between the two populations.

NCT ID: NCT03763071 Completed - Pregnancy Clinical Trials

Sleep Disturbances in the 2nd and 3rd Trimester

Start date: December 7, 2018
Phase:
Study type: Observational

Sleep disorders and disturbances are mostly underestimated in clinical practice. Moreover, this problem is generally neglected by the pregnant themselves. Today, it is important to underline any problem that may have an affect to improve the quality of life during pregnancy. This study assesses the sleep quality, insomnia patterns and obstructive sleep apnea in the second and third trimesters of pregnancy.

NCT ID: NCT03760341 Completed - Clinical trials for Obstructive Sleep Apnea

Cold Versus Hot Adenoidectomy for Obstructive Sleep Apnea in Pediatric Patients

Start date: October 1, 2014
Phase: N/A
Study type: Interventional

Background: Adenoidectomy is one of the most common procedures done by the otolaryngologist. The procedure can be performed using the cold method (mainly adenoid curettes) or the hot method (suction diathermy). Both techniques have similar intra and post-operative outcomes. However, the long term clinical outcome in improving the sleep disorder symptoms was never compared between the two methods. Objective: To compare the advantages using the hot method compared to the cold method adenoidectomy in the long term follow up. Methods: A prospective, randomized, single blinded study of children undergoing adenoidectomy between the years 2014-2017. Patients were randomized to hot or cold adenoidectomy techniques. The primary outcome was change of the Pediatric Sleep Questionnaire Score (PSQ) scores one month and one year after surgery.