Clinical Trials Logo
  1. Home
  2. Sexually Transmitted Infections
  3. NCT00713999

Urogenital Schistosomiasis and Sexually Transmitted Infections in Madagascar — FGS/MGS/STI  

Sexually Transmitted Infections Clinical Trial

Official title:
Study of Reproductive Health in Rural Madagascar With Emphasis on Urogenital Schistosomiasis and Sexually Transmitted Infections

Clinical Trial Summary

A cross-sectional study of urogenital schistosomiasis and sexually transmitted infections (STI) prevalence and associated morbidity in a rural community in Madagascar. Clearance of infections and resolution of morbidity were subsequently studied in two phases following systematic anti-STI and anti-schistosoma treatment, respectively.

Clinical Trial Description

The study was conducted in the Schistosoma haematobium high-endemic SIRAMA sugarcane plantation near the Ambilobe town in the northern province of Diego Suarez in Madagascar. A neighboring low-endemic village, Mataipako, was selected a control village. Participants aged 15 to 49 years old from SIRAMA were included in the study if positive for S.haematobium egg in urine.

A questionnaire addressing previous medical history and current urogenital symptoms was applied. A physical examination, including ultrasonophical (US) examination of urinary tract by transabdominal route, was undertaken. A pelvic examination, including transvaginal US was performed in women. In men, the prostate and the seminal vesicles were examined by transrectal US.

The following sexually transmitted infections (STI) were systematically assessed:

- Neisseria gonorrheae

- Chlamydia trachomatis

- Mycoplasma genitalium

- Trichomonas

- Treponema pallidum

- Herpes simplex 1 and 2

After baseline assessment, all participants (and partners) were systematically treated with an anti-STI regimen according to the existing guidelines by the Ministry of Health in Madagascar.

Re-assessment by questionnaire, physical examination and sampling for STIs was undertaken 4 weeks later followed by systematic praziquantel treatment to general community, including study participants.

A final follow-up study following the baseline protocol was conducted 5 months later. ;

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00713999
Study type Interventional
Source University of Aarhus
Contact
Status Completed
Phase N/A
Start date August 2001
Completion date September 2003
View Details
See also
  Status Clinical Trial Phase
Completed NCT01144871 - Parental Knowledge and Attitudes of Confidential Sexually Transmitted Infections (STI) Services for Teens N/A
Completed NCT04661566 - Optimizing a Multi-Modal Intervention to Reduce Health-Risking Sexual Behaviors: Component Selection N/A
Completed NCT01842100 - To Compare the Strategies of Universal Antibiotic Prophylaxis Versus Screen-and-treat in Reducing Infective Complications and Re-infection in Women Who Undergo Termination of Pregnancy N/A
Completed NCT04867798 - Transgender Men and HIV in Uganda: PrEP Uptake and Persistence
Active, not recruiting NCT04328025 - Peer-Delivered HIV Self-Testing, STI Self-Sampling and PrEP for Transgender Women in Uganda N/A
Completed NCT02509572 - Improvement of STI Detection in Adolescent Emergency Department Patients N/A
Active, not recruiting NCT04758390 - A Comprehensive HIV Prevention Package for South African Adolescent Girls and Young Women N/A
Completed NCT03528135 - Project PRIDE (Promoting Resilience In Discriminatory Environments) N/A
Recruiting NCT04547413 - STI/HIV Intervention Behavioral Intervention Program N/A
Completed NCT02461940 - STI/HIV Prevention Intervention for Adolescents in Singapore N/A
Completed NCT01784809 - The Multimedia HIV/STI Prevention for Drug-Involved Female Offenders Phase 2
Completed NCT01136850 - Intermittent Preventive Treatment With Azithromycin-containing Regimens in Pregnant Women in Papua New Guinea Phase 3
Completed NCT00469547 - 62% & 15% Ethanol in Emollient Gel as Topical Male Microbicides Phase 1
Completed NCT01285349 - HIV/STI Prevention for Drug-Involved Couples N/A
Completed NCT02391233 - Multimedia WORTH With Black Drug-Involved Women on Probation N/A
Completed NCT02183909 - Connecting Resources for Urban Sexual Health N/A
Completed NCT02882607 - Peer Groups for Healthy Pregnancy & HIV Prevention for Young Malawian Women N/A
Completed NCT00362375 - Evaluation of the Healthy Love Workshop, an HIV Prevention Intervention for African American Women Phase 1/Phase 2
Active, not recruiting NCT04710784 - A Pragmatic Trial to Expand Youth-friendly HIV Self-testing N/A
Recruiting NCT06223165 - Optimizing the Floreciendo Sexual and Reproductive Health Workshop for Latina Teens and Female Caregivers: A Pilot N/A