Thigh Muscle Mass and Muscle Wasting in Patients in the Emergency Department

Sepsis Clinical Trial

Official title:

Thigh Muscle Mass and Muscle Wasting in Patients in the Emergency Department

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05978154
• Other study ID #: musclemassandwastingined
• Status: Recruiting
• Start date: July 28, 2023
• Est. completion date: March 31, 2025

Study information

• Verified date: July 2023
• Source: Korea University Ansan Hospital
• Contact: Sejoong Ahn
• Phone: 82-10-2946-0250
• Email: sejongahn[@]naver.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The goal of this observational study is to evaluate whether thigh muscle mass and muscle wasting are associated with mortality in patients who visit the emergency department. The main questions it aims to answer are: - Is thigh muscle mass associated with mortality in patient who visit the emergency department? - Does muscle wasting exist during staying in the emergency department? - Is muscle wasting associated with mortality in patient who visit the emergency department? Participants will be evaluated for serial thigh muscle mass using point-of-care ultrasound at the emergency department.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 600
• Est. completion date: March 31, 2025
• Est. primary completion date: December 31, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 19 Years to 80 Years

Eligibility

Inclusion Criteria:

• patients who visit the emergency department of Korea University Ansan Hospital during study period
• patients with age within the limits
• patients who are willing to be participate the study with informed consent
• patients who undergo point-of-care ultrasound to evaluate thigh muscle mass

Exclusion Criteria:

• patients with age out of limits
• patients who have deformities on lower leg
• patients who is unable to maintain appropriate position to undergo point-of-care ultrasound
• patients who decline to participate the study
• patients who have 'do-not-resuscitate' order or are not willing to be resuscitated
• patients of whom point-of-care ultrasound on thigh muscle mass was not performed

Related Conditions & MeSH terms

• Acute Respiratory Failure
• Cardiac Arrest
• Emergencies
• Muscular Atrophy
• Respiratory Insufficiency
• Sepsis
• Shock
• Trauma

Intervention

Other:
• Thigh muscle mass and muscle wasting (exposure)
Thigh muscle mass and muscle wasting (exposure variable)

Locations

Country	Name	City	State
Korea, Republic of	Korea University Ansan Hospital	Ansan-si	Gyeonggi-do

Sponsors (1)

Lead Sponsor	Collaborator
Korea University Ansan Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	28 day mortality	28 day mortality	28 days after study enrollment