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Effect of Probiotics and Prebiotics in Renal Function in Septic Acute Kidney Injury Patients

Sepsis Clinical Trial

Official title:
Effect of Probiotics and Prebiotics in Renal Function in Septic Acute Kidney Injury Patients, Randomized Control Trial

Clinical Trial Summary

Septic acute kidney injury is a condition associated with highly related to inflammatory molecules. Prebiotics and probiotics have shown to improve inflammatory cascade in animal model; In this study, the investigators propose the use of probiotics to improve the clinical evolution of septic acute kidney injury patients.

Clinical Trial Description

Acute kidney injury is most commonly caused by sepsis, where endotoxemia and an expanding inflammatory reaction play a key role in its pathogenesis, when this condition is present it is highly related to poor clinical outcomes and higher mortality rates. There is no current specific treatment, and the therapeutic approach is more orientated to complication management. In this study, the investigators propose the use of probiotics to improve the clinical evolution of septic acute kidney injury patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03877081
Study type Interventional
Source Hospital Civil de Guadalajara
Contact
Status Recruiting
Phase Phase 3
Start date January 4, 2019
Completion date February 4, 2023
View Details
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