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Insight Into Hippocampal Neuroplasticity in Schizophrenia by Investigating Molecular Pathways During Physical Training — BrainTrain  

Schizophrenia Clinical Trial

Official title:
Insight Into Hippocampal Neuroplasticity in Schizophrenia by Investigating Molecular Pathways During Physical Training

Clinical Trial Summary

Aerobic endurance training has shown positive effects on symptoms, cognition, daily functioning, and the structure of the hippocampus in patients with schizophrenia. The study investigates genetic and epigenetic influences on neuroplastic changes following three months of endurance training. A control group performs flexibility, strength, and balance training. The main objective is to examine the association between a genetic risk score for schizophrenia and volume increase in the CA4/DG region of the hippocampus. Additional goals include examining changes in synapses, brain structure, function, and metabolism, as well as clinical symptoms and cognitive performance.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05956327
Study type Interventional
Source LMU Klinikum
Contact Isabel Maurus, Dr.
Phone +49 89 4400 55537
Email Isabel.Maurus@med.uni-muenchen.de
Status Recruiting
Phase N/A
Start date September 29, 2023
Completion date September 2026
View Details
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