Neurobiological Effects of Oxytocin in Schizophrenia

Status Recruiting

Clinical Trial Summary

22 male patients with schizophrenia and 22 male healthy volunteers will be included in the study. Subjects who meet the inclusion and exclusion criteria for the study will be recruited. After completion of clinical assessments and neuropsychological assessments, all subjects will undergo two multi-modal imaging sessions. In one scan they will receive intranasal oxytocin and in another scan will receive intranasal saline as control. The order of administration of the medication will be counterbalanced and subjects will be blind to the medication administered. Using the simultaneous PET-MRI scanner, PET and fMRI data will be collected simultaneously. Blood will be collected for analysis of oxytocin receptor gene polymorphism and its potential effect on brain activity.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Schizophrenia

Clinical Trial Details

NCT number	NCT04177719
Study type	Interventional
Source	National Institute of Mental Health and Neuro Sciences, India
Contact	Naren P Rao, MD
Phone	08026995879
Email	narenrao@nimhans.ac.in
Status	Recruiting
Phase	N/A
Start date	November 8, 2019
Completion date	April 2022

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