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Naltrexone and Bupropion Combination on Obese,Smoking Patients With Schizophrenia

Schizophrenia Clinical Trial

Official title:
Effect of Naltrexone and Bupropion Combination on Weight Loss and Smoking Cessation in Obese, Cigarette-smoking Patients With Schizophrenia

Clinical Trial Summary

The purpose of this research is to observe the efficacy of Naltrexone and Bupropion combination on weight loss and smoking cessation from baseline to week 24 compare to placebo.

Clinical Trial Description

This is a randomized, double-blind, and placebo-controlled study. Subjects with evaluation and confirmation that inclusion and exclusion criteria are met, will be treated with naltrexone sustained release 15mg once per day and bupropion sustained release 150mg once per day in the first two weeks, and naltrexone 25mg once per day and bupropion 300mg once per day during the rest of the study.The purpose of this research is to observe the efficacy of Naltrexone and Bupropion on weight loss and smoking cessation compared to placebo. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02736474
Study type Interventional
Source Shanghai Mental Health Center
Contact
Status Completed
Phase Phase 4
Start date May 2016
Completion date July 2018
View Details
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