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Retinoic Acid Homeostasis in Neuropsychiatric Diseases — RAHND  

Schizophrenia Clinical Trial

Official title:
Retinoic Acid Homeostasis in Neuropsychiatric Diseases

Clinical Trial Summary

It is hypothesized, that local retinoic acid (RA) homeostasis is functionally involved in the pathophysiology of depression. In a cross-sectional (and partly longitudinal) analysis, serum RA status will be assessed in healthy controls and subjects with Major Depression, Alzheimer's disease, alcoholism and in subjects with schizophrenia.

Clinical Trial Description

Retinoids comprise of a group of small-molecule derivatives of Vitamin A with retinoic acid (RA) representing the biologically most active endogenous form. RA has multiple functions central nervous system (CNS). It is hypothesized, that local RA homeostasis is functionally involved in the pathophysiology of numerous neuropsychiatric diseases. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02439099
Study type Observational
Source Charite University, Berlin, Germany
Contact Julian Hellmann-Regen, MD
Email Julian.Hellmann@charite.de
Status Recruiting
Phase
Start date March 2015
Completion date December 2022
View Details
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