Schizophrenia Clinical Trial
NCT number | NCT02248987 |
Other study ID # | 3420130030 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | May 2014 |
Est. completion date | May 2016 |
Verified date | April 2019 |
Source | Seoul National University Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The purpose of this study is to evaluate abnormal dopamine synthesis and connectivity according to the antipsychotic treatment response in schizophrenia.
Status | Completed |
Enrollment | 36 |
Est. completion date | May 2016 |
Est. primary completion date | May 2016 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 20 Years to 55 Years |
Eligibility |
Inclusion Criteria: - diagnosis of schizophrenia - clinically stable state Exclusion Criteria: - history of previous head injury, epileptic disorder, other medical comorbidity - substance abuse/dependence |
Country | Name | City | State |
---|---|---|---|
Korea, Republic of | Seoul National University Hospital | Seoul |
Lead Sponsor | Collaborator |
---|---|
Seoul National University Hospital |
Korea, Republic of,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Striatal [18F]-DOPA uptake measured using positron emission tomographic 18F-dopa imaging. | within 2 weeks from enrollment | ||
Secondary | resting state functional magnetic resonance imaging | within 2 weeks from enrollment | ||
Secondary | diffusion tensor imaging | within 2 weeks from enrollment | ||
Secondary | clinical measure including Positive and Negative Syndrome Scale | within 2 weeks from enrollment | ||
Secondary | neurocognitive function test | within 2 weeks from enrollment |
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