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Effects of Paliperidone Palmitate Versus Oral Antipsychotics on Clinical Outcomes and MRI Measures

Schizophrenia Clinical Trial

Official title:
Effects of Paliperidone Palmitate Versus Oral Antipsychotics on Clinical Outcome and sMR Measures in First Episode Patients: A Randomized Clinical Trial

Clinical Trial Summary

The primary objective of this study is to compare the effects of paliperidone versus oral antipsychotics on changes in brain parenchymal volume, number of relapses, and time to relapse during a one-year period of follow up of patients with new onset schizophrenia.

Clinical Trial Description

Subjects will participate in 1 year of treatment with 3 MRI scans at six month intervals. Side effects and metabolic measures will be followed over the course of the study. ;

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Caregiver), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01359293
Study type Interventional
Source University of Iowa
Contact Frank W Fleming, BS, BSN, RN
Phone 319-356-4719
Email frank-fleming@uiowa.edu
Status Recruiting
Phase N/A
Start date April 2011
Completion date December 2014
View Details
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