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NCT01295411 Clinical Trial

Morphological, Structural and Functional Neural Substrates of Quality of Life in Schizophrenia

Schizophrenia Clinical Trial

Official title:
Morphological, Structural and Functional Neural Substrates of Quality of Life in Schizophrenia

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT01295411
Other study ID # 2010-A01421-38
Secondary ID 2010-29
Status Active, not recruiting
Phase N/A
First received February 9, 2011
Last updated April 27, 2015
Start date January 2011
Est. completion date September 2015

Study information
Verified date April 2015
Source Assistance Publique Hopitaux De Marseille
Contact n/a
Is FDA regulated No
Health authority France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)
Study type Interventional

Clinical Trial Summary

The aim of the investigators analysis is to identify the neural correlates of quality of life scores in schizophrenia. For this, the investigators will constitute group of patients according to their quality of life scores and the investigators will analyze their differences in patterns of brain structures and activations.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 100
Est. completion date September 2015
Est. primary completion date January 2015
Accepts healthy volunteers No
Gender Both
Age group 18 Years to 40 Years
Eligibility Inclusion Criteria:

- diagnosis of schizophrenia according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria (American Psychiatric Association(APA), 1994),

- age over 18 years,

- informed consent to participate in the studies

- French as native language

Exclusion Criteria:

- diagnosis other than schizophrenia on Axis I of DSM-IV,

- decompensated organic disease and mental retardation

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label

Related Conditions & MeSH terms

Intervention

Device:
• Magnetic Resonance Imaging

Other:
• EVALUATION NEUROPSYCHOLOGICAL

Locations
Country Name City State
France Assistance Publique Hopitaux de Marseille Marseille

Sponsors (1)
Lead Sponsor Collaborator
Assistance Publique Hopitaux De Marseille

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary to study the relationships between quality of life and the morphologic, structural and functional substrates in schizophrenia 36 months No
Secondary to determine whether quality of life is correlated with brain modifications using functional Magnetic Resonance Imaging 36 months No
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