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NCT00692679 Clinical Trial

FMRI of Cholinergic Mechanisms in Schizophrenia

Schizophrenia Clinical Trial

Official title:
FMRI of Cholinergic Mechanisms in Schizophrenia

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT00692679
Other study ID # 07-1261
Secondary ID
Status Not yet recruiting
Phase N/A
First received June 3, 2008
Last updated July 25, 2012
Start date May 2010

Study information
Verified date July 2012
Source VA Eastern Colorado Health Care System
Contact n/a
Is FDA regulated No
Health authority United States: Federal Government
Study type Observational

Clinical Trial Summary

This study will examine brain responses during sensory processing in patients with schizophrenia. It will examine the hypothesis that patients treated with clozapine will show decreased responses during sensory processing as compared to patients treated with risperidone.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 40
Est. completion date
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years to 65 Years
Eligibility Inclusion Criteria:

- Diagnosis of schizophrenia

- treatment with clozapine or risperidone

Exclusion Criteria:

- Metal in body including pacemaker, aneurism clip, weight over 300 lbs

Study Design

Observational Model: Cohort, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Locations
Country Name City State
United States Dept. of Veterans Affairs Medical Center Denver Colorado
United States University of Colorado Denver Medical School Denver Colorado

Sponsors (1)
Lead Sponsor Collaborator
VA Eastern Colorado Health Care System

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary BOLD FMRI response in hippocampus Various No
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