Schizophrenia Clinical Trial
Official title:
A Double Blind Randomized Controlled Trial to Explore the Tolerability, Safety and Efficacy of the H-Coil Deep Transcranial Magnetic Stimulation (TMS) in Subjects With Negative Symptoms and Cognitive Deficits of Schizophrenia
Objectives:The purpose of the study is to explore the efficacy and safety of H1-Coil deep
brain rTMS in subjects with negative symptoms and cognitive deficits of schizophrenia
(deficit syndrome), currently treated with atypical antipsychotics.
Patient Population: The intention is to treat 45 patients diagnosed with schizophrenia, who
are currently suffering mainly from negative symptoms and cognitive deficits (deficit
syndrome). The patients will be of all racial, ethnic and gender categories, ranging from 18
to 65 years of age, and have PANSS negative≥21 and PANSS positive<24. Patients will be
recruited from both academic and private research centers.
Structure: The study is a randomized, prospective, 8 weeks, double blind study. Blinding:
The treatment administrator and the study personnel and patients will be masked to the
treatment being administrated.
Concurrent Control: The study group will receive active rTMS treatment and the control group
will receive an inactive, sham treatment.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
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