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NCT00237861 Clinical Trial

Effectiveness of Atypical Versus Conventional Antipsychotics in Treating Schizophrenia

Schizophrenia Clinical Trial

Official title:
Effectiveness of Atypical Vs Conventional Antipsychotics

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00237861
Other study ID # MH57292
Secondary ID R01MH057292
Status Completed
Phase Phase 4
First received October 7, 2005
Last updated June 5, 2014

Study information
Verified date June 2014
Source Yale University
Contact n/a
Is FDA regulated No
Health authority United States: Federal Government
Study type Interventional

Clinical Trial Summary

This study will compare the effectiveness of newer atypical antipsychotics versus older conventional antipsychotics in treating schizophrenia.

Description:

At seven participating hospitals, acutely exacerbated patients with schizophrenia were randomly assigned to treatment with antipsychotic from the atypical class vs antipsychotic from the conventional class. Medication choice within class, dose, concomitant medications, and other prescribing decisions were left to the community prescriber. Patients were followed for one year after discharge.

Recruitment information / eligibility
Status Completed
Enrollment 0
Est. completion date
Est. primary completion date December 2002
Accepts healthy volunteers No
Gender Both
Age group N/A and older
Eligibility Inclusion Criteria:

- hospitalized for schizophrenia

Exclusion Criteria:

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Drug:
• risperidone

• olanzapine

• quetiapine

Locations
Country Name City State
n/a

Sponsors (2)
Lead Sponsor Collaborator
Yale University National Institute of Mental Health (NIMH)

Outcome
Type Measure Description Time frame Safety issue
Primary PANSS
Primary Retention.
Secondary EPS, TD.
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