Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults

Sarcopenia Clinical Trial

Official title:

Prevalence of Sarcopenia and Sarcopenic Obesity in Community-dwelling Outpatient Older Adults

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04122638
• Other study ID #: GoztepeTRH
• Status: Completed
• Start date: October 7, 2019
• Est. completion date: January 1, 2020

Study information

• Verified date: February 2020
• Source: Goztepe Training and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Syndromes such as sarcopenia, sarcopenic obesity and osteosarcopenic obesity are commonly seen in older adults. They result from the impairment of muscle, bone and adipose tissue. Thus, they lead to a decrease in quality of life and increase morbidity and mortality. The aim of this study is to report the prevalence of sarcopenia, sarcopenic obesity and osteosarcopenic obesity in community-dwelling outpatient older adults and to investigate the related factors.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 572
• Est. completion date: January 1, 2020
• Est. primary completion date: January 1, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• Being at the age of 65 or older

• Being able to complete 4-m walk test

Exclusion Criteria:

• <24 points on Mini-Mental State Examination

• 12 points or higher on Geriatric Depression Scale

Related Conditions & MeSH terms

• Bone Diseases, Metabolic
• Obesity
• Osteopenia, Osteoporosis
• Osteoporosis
• Sarcopenia
• Sarcopenic Obesity

Locations

Country	Name	City	State
Turkey	Goztepe Training and Research Hospital	Istanbul

Sponsors (3)

Lead Sponsor	Collaborator
Goztepe Training and Research Hospital	Istanbul Medeniyet University, Istanbul University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Handgrip Strength	Handgrip strength measured by Takei© Hand Dynamometer	10 minutes
Primary	Muscle mass	Using Bioimpedance analysis (BIA) technique with TANITA© TBF 300	5 minutes
Primary	Bone density	T score evaluation using Dual-energy X-ray absorptiometry (DEXA)	30 minutes
Primary	Percentage of body fat	Using Bioimpedance analysis (BIA) technique with TANITA© TBF 300	5 minutes
Secondary	Gait speed	4-m usual walking speed test	3 minutes
Secondary	Physical Activity	Using Rapid Assessment of Physical Activity (RAPA)	5-10 minutes
Secondary	Nutritional Status	Assessed with Mini-Nutritional Assessment (MNA)	10 minutes
Secondary	Activities of Daily Living	Activities of daily living assessed with Katz Index of Independence in Activities of Daily Living	10 minutes
Secondary	Instrumental Activities of Daily Living	Instrumental activities of daily living assessed with Lawton -Brody Instrumental Activities of Daily Living Scale	10 minutes
Secondary	Depression	Assessed with The Geriatric Depression Scale- Short Form	10 minutes
Secondary	Mini-Mental State Examination	Mini-Mental State Examination	10-15 minutes
Secondary	Blood Sample Analysis	A blood sample analysis including parameters such as: wbc, hgb, htc, mcv ,plt, fasting blood sugar, urea, uric acid, creatin, AST, ALP, ALT, GGT, LDH, total colesterol, trigylicerid, LDL, HDL, NA, K, Mg, Ca, P, Albumin, protrombin time, CRP, B12, folate, iron, ferritin, PTH, vitamin-D, sedimentation, TSH, T4, insukin, HGBA1C, IHOMA-IR.	5 minutes
Secondary	Comorbidities	Assessed with Charlson Comorbidity Index	5 minutes