Clinical Trials Logo
  1. Home
  2. Rhizarthrosis
  3. NCT04829565

Assessment of Pain After Intra-articular Botulinum Toxin Injections in Carpometacarpal Osteoarthritis of the Thumb

Rhizarthrosis Clinical Trial

Official title:
Assessment of Pain After Intra-articular Botulinum Toxin Injections in Carpometacarpal Osteoarthritis of the Thumb

Clinical Trial Summary

Only 4 randomized controlled clinical trials have been published to date to assess the short-term effectiveness of intra-articular Botulinum Toxin injection on pain, function and quality of life in patients suffering from chronic knee pain related or not to knee osteoarthritis and also in the context of ankle osteoarthritis. The analgesic properties and the reported safety make intra-articular Botulinum toxin a strong candidate in the treatment of symptomatic manifestations of osteoarthritis disease and more particularly in certain locations such as the trapezo-metacarpal joint. Investigators hypothesize that injection of intra-articular Botulinum toxin into the trapezo-metacarpal joint will be of benefit in reducing pain and improving function in patients with rhizarthrosis. Investigators will begin a monocentric randomized controlled trial comparing intra-articular injections of Botulinum toxin and placebo.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04829565
Study type Interventional
Source Centre Hospitalier Universitaire de Nice
Contact Pierre Blanc
Phone 0492039655
Email blanc.p@chu-nice.fr
Status Recruiting
Phase Phase 4
Start date September 9, 2021
Completion date August 15, 2025
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05047744 - Dual Mobility Total Joint Prosthesis (Touch) for Thumb Carpometacarpal Joint Osteoarthritis N/A
Active, not recruiting NCT04115085 - Study of Medical Ultrasound for Rhizarthrosis N/A
Recruiting NCT06078189 - Rhizarthrosis Surgery and Functional Recovery: Arthroplasty vs. Trapezectomy
Completed NCT03320291 - Long-term Evaluation of Primary Trapeziectomy and Placement of a RegJoint Implant in the Treatment of Rhizarthrosis N/A
Completed NCT04587570 - Rhizarthrosis Study N/A
Completed NCT02676284 - Durolane SJ for Treatment of Rhizarthrosis N/A
Recruiting NCT05597930 - New 3D Printed Wrist Orthosis N/A
Completed NCT03431584 - Effects on the Pain of an Infiltration by Acid Hyaluronic Association and Corticoids Versus Only Corticoids in the Rhizarthrosis. Phase 4
Active, not recruiting NCT03089723 - Saline Lavage X Saline Lavage and Osteonil® Mini in Rizarthritis N/A
Recruiting NCT01233739 - Chondroitin Sulphate Treatment Efficacy in Rhizarthrosis. Phase 4
Completed NCT05915962 - Biological Characterization Study of an Autograft Nanofat (Nanocarabio) N/A
Not yet recruiting NCT04588961 - Trapeziectomy Suspensionplasty Versus Carpometacarpal Joint Replacement in Treatment of Basal Thumb Osteoarthritis N/A
Terminated NCT03020368 - Effectiveness and Safety of Breeded Leech for Symptomatic Primary Arthrosis of the First Carpometacarpal Joint N/A
Completed NCT05169099 - Post-operative Results of the Trapezometacarpal (TMC) Prosthesis for Advanced Pre-operative Deformities
Recruiting NCT03879434 - Routine Application of Ostenil® Mini in Patients With Rhizarthrosis
Not yet recruiting NCT05708430 - Tolerance of Intra-articular Injection Autologous Stromal Vascular Fraction for the Treatment of Rhizarthrosis Phase 2