Clinical Trials Logo
  1. Home
  2. Rhizarthrosis
  3. NCT04587570

Rhizarthrosis Study — RHI  

Rhizarthrosis Clinical Trial

Official title:
Injection of Platelet Rich Plasma and Autologous Fat Into the Thumb Carpometacarpal Joint for the Evaluation Their Potential Filling Effect in Patients With Osteoarthritis

Clinical Trial Summary

Rhizarthrosis is the wear of the thumb saddle joint. It is a very common disease affecting up to 25% of postmenopausal women. There are currently various conservative and surgical methods available for treatment. If conservative treatment does not lead to freedom from pain, one of the surgical methods can be used, such as metacarpal extension osteotomy, trapeziectomy with or without ligamentoplasty, trapeziometacarpal arthrodesis, prosthesis implantation and various forms of interposition arthroplasty . Despite the high satisfaction rate of up to 95% after surgical treatment, the anatomy of the carpus is irreversibly destroyed . Apart from that, these operations are also associated with corresponding complications and post-operative immobilization of several weeks. Thus, a minimally invasive treatment method with a corresponding success rate would be of great advantage. Hypothesis: By infiltrating and filling the joint with Platelet-Rich Plasma (PRP), fat or a combination of both, the pain of rhizarthrosis can be reduced. Aim of the study: The aim of the announced doctoral thesis is to investigate the effect of PRP, lipofilling and its combination on arthroses of the thumb saddle joint after a single joint injection and to compare it with a control group.It is to be proven that PRP, fat and their combination lead to a different degree of pain relief compared to the control group due to the expansion of the joint space and the associated filling effect.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04587570
Study type Interventional
Source Medical University of Graz
Contact
Status Completed
Phase N/A
Start date May 22, 2017
Completion date November 8, 2021
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT04829565 - Assessment of Pain After Intra-articular Botulinum Toxin Injections in Carpometacarpal Osteoarthritis of the Thumb Phase 4
Recruiting NCT05047744 - Dual Mobility Total Joint Prosthesis (Touch) for Thumb Carpometacarpal Joint Osteoarthritis N/A
Active, not recruiting NCT04115085 - Study of Medical Ultrasound for Rhizarthrosis N/A
Recruiting NCT06078189 - Rhizarthrosis Surgery and Functional Recovery: Arthroplasty vs. Trapezectomy
Completed NCT03320291 - Long-term Evaluation of Primary Trapeziectomy and Placement of a RegJoint Implant in the Treatment of Rhizarthrosis N/A
Completed NCT02676284 - Durolane SJ for Treatment of Rhizarthrosis N/A
Recruiting NCT05597930 - New 3D Printed Wrist Orthosis N/A
Completed NCT03431584 - Effects on the Pain of an Infiltration by Acid Hyaluronic Association and Corticoids Versus Only Corticoids in the Rhizarthrosis. Phase 4
Active, not recruiting NCT03089723 - Saline Lavage X Saline Lavage and Osteonil® Mini in Rizarthritis N/A
Recruiting NCT01233739 - Chondroitin Sulphate Treatment Efficacy in Rhizarthrosis. Phase 4
Completed NCT05915962 - Biological Characterization Study of an Autograft Nanofat (Nanocarabio) N/A
Not yet recruiting NCT04588961 - Trapeziectomy Suspensionplasty Versus Carpometacarpal Joint Replacement in Treatment of Basal Thumb Osteoarthritis N/A
Terminated NCT03020368 - Effectiveness and Safety of Breeded Leech for Symptomatic Primary Arthrosis of the First Carpometacarpal Joint N/A
Completed NCT05169099 - Post-operative Results of the Trapezometacarpal (TMC) Prosthesis for Advanced Pre-operative Deformities
Recruiting NCT03879434 - Routine Application of Ostenil® Mini in Patients With Rhizarthrosis
Not yet recruiting NCT05708430 - Tolerance of Intra-articular Injection Autologous Stromal Vascular Fraction for the Treatment of Rhizarthrosis Phase 2