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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03281863
Other study ID # AssiutU71516
Secondary ID
Status Completed
Phase
First received
Last updated
Start date October 1, 2018
Est. completion date March 24, 2020

Study information

Verified date March 2021
Source Assiut University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

clinical audit on the Managment of rheumatic fever in assiut university children hospital.


Description:

Acute rheumatic fever,an auto immune response to Group A streptococcus infection of the upper respiratory tract,may result in carditis.when the inflammation leads to permenant damage of the valves the individual has rheumatic heart disease. Recurrences of rheumatic fever are likely in the absence of preventive measures and may cause further cardiac valve and muscle damage,leading to heart failure,stroke and premature death.bacterial endocarditis is also a complication.


Recruitment information / eligibility

Status Completed
Enrollment 100
Est. completion date March 24, 2020
Est. primary completion date March 24, 2020
Accepts healthy volunteers No
Gender All
Age group 5 Years to 15 Years
Eligibility Inclusion Criteria: - patients with confirmed diagnosis of rheumatic fever based on laboratory investigations. Exclusion Criteria: - No

Study Design


Related Conditions & MeSH terms


Intervention

Diagnostic Test:
C reactive protein, anti streptolysin o antibody test ,erythrocyte sedimentation rate
Throat culture to detect the causative organism

Locations

Country Name City State
Egypt Egypt Assiut

Sponsors (1)

Lead Sponsor Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome

Type Measure Description Time frame Safety issue
Primary laboratory investigations (ASOt , ESR . CRP) laboratory investigations that measure the inflammation process will be used and the target that the ASOt not increase 1/400 One year from October 2017 to september 2018
Secondary clinical measures improvement of arthritis if found One year from October 2017 to september 2018
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