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Respiratory Failure clinical trials

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NCT ID: NCT01238757 Completed - Respiratory Failure Clinical Trials

Patient-ventilator Asynchrony During Mechanical Non-Invasive Assisted-ventilation in Pediatric Patients (NavPed-NI)

NavPed-NI
Start date: June 2010
Phase: N/A
Study type: Interventional

The purpose of this study is - to document the prevalence and type of asynchronies incidence during non-invasive mechanical ventilation in pediatric patients breathing under pressure support. - to observe the impact of adjusting the expiratory trigger setting on asynchronies during pressure support - and compare these incidences with asynchronies measured in pediatric patient breathing under NAVA system (Neurally Adjusted Ventilatory Assist).

NCT ID: NCT01204281 Completed - Respiratory Failure Clinical Trials

Proportional Assist Ventilation (PAV) in Early Stage of Critically Ill Patients

Start date: September 2010
Phase: Phase 4
Study type: Interventional

To evaluate the effectiveness of high assistance proportional assist ventilation (PAV+) (objective 80% gain) as main ventilatory support in early stage of critically ill patients in comparison with standard volume-assist control ventilation (ACV).

NCT ID: NCT01160978 Completed - Heart Failure Clinical Trials

Donor Simvastatin Treatment in Organ Transplantation

SIMVA
Start date: June 1, 2010
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of the study is to investigate the effects of donor simvastatin treatment on ischemia-reperfusion injury after heart transplantation.

NCT ID: NCT01136109 Completed - Respiratory Failure Clinical Trials

A Study to Evaluate the Effect of Mechanical Ventilation on the Inferior Vena Cava Collapsibility Index

IVCCI
Start date: October 2009
Phase:
Study type: Observational

Previous research has shown that the Inferior Vena Cava Collapsibility Index (IVCCI) can be used to assess volume status. One limitation of the previous work is that changes in intra-thoracic pressure can influence this measurement, and the magnitude of this effect has never been described. The investigators aim is to correlate the degree of change in IVCCI with the set degree of change in intra-thoracic pressure in a heterogeneous population of critically ill patients.

NCT ID: NCT01111578 Completed - Respiratory Failure Clinical Trials

Evaluation of a New Enteral Feeding Tube for the Measurement of Esophageal and Gastric Pressure

Start date: November 2009
Phase: N/A
Study type: Observational

Investigators aim to evaluate the accuracy in the measurement of the esophageal and gastric pressure of a new enteral feeding tube

NCT ID: NCT01108575 Completed - Respiratory Failure Clinical Trials

Effect of Inspiratory Muscle Training on Duration of Mechanical Ventilation Support

Start date: May 2010
Phase: Phase 1/Phase 2
Study type: Interventional

A growing body of knowledge has documented that the diaphragm, the primary muscle of breathing, atrophies and weakens within days of instituting mechanical ventilation support. Diaphragm weakness has been implicated as a major contributor to difficulty with weaning, or breathing without ventilator support. This study will test whether instituting a diaphragm strength training rehabilitation program will reduce the time patients require mechanical ventilation in a surgical intensive care setting.

NCT ID: NCT01065428 Completed - Respiratory Failure Clinical Trials

Extubation Readiness and Neuroventilatory Efficiency After Acute Respiratory Failure

Start date: December 2008
Phase: Phase 1
Study type: Observational

The aim of this study was to compare the indices of rapid shallow breathing, neuromechanical efficiency (NME), and neuroventilatory efficiency (NVE) between patients being successfully extubated and those who failed weaning.

NCT ID: NCT01056952 Completed - Respiratory Failure Clinical Trials

Physiologic Effects of High Flow Nasal Therapy in Patients With Acute Hypoxemic Respiratory Failure (OPTIFLOW)

Start date: January 2010
Phase: N/A
Study type: Interventional

The aim of the study is to assess, in patients with acute hypoxemic respiratory failure, the short term physiologic effects of the high flow oxygen nasal therapy (Optiflow), in term of inspiratory muscle effort, gas exchange, comfort and dyspnea

NCT ID: NCT01054183 Completed - Respiratory Failure Clinical Trials

The Use of the GlideScope Ranger in Pediatric Critical Care Transport

Start date: July 2010
Phase: N/A
Study type: Interventional

This study seeks to assess the role of the GlideScope Ranger video laryngoscope in facilitating successful neonatal/pediatric intubation by pediatric critical care transport teams. The central hypothesis of this study is that the GlideScope Ranger video laryngoscope reduces the rates of failed intubation attempts by pediatric critical care transport teams. The aims of this project are designed to specifically: (1) Establish competencies for GlideScope Ranger video laryngoscopy-assisted intubation for pediatric and neonatal patients; and (2) Compare the intubation success rates for intubation using GlideScope Ranger video laryngoscopy and using conventional, direct laryngoscopy by pediatric and neonatal critical care transport teams.

NCT ID: NCT01047852 Completed - Respiratory Failure Clinical Trials

Noninvasive Ventilation After Extubation in Hypercapnic Patients

VHYPER
Start date: January 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the efficacy of noninvasive ventilation (NIV) in the prevention of extubation failure and mortality in patients with either chronic respiratory disorders or hypercapnic respiratory failure during spontaneous breathing.