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Respiratory Aspiration clinical trials

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NCT ID: NCT03780387 Terminated - Asthma Atopic Clinical Trials

Identification of Allergic Asthmatics Reactive to Felis Catus (Cat Hair) Allergen Inhalation

Start date: April 16, 2019
Phase: Early Phase 1
Study type: Interventional

This study is designed to identify Felis Catus, or cat hair, sensitive asthmatics who demonstrate a late phase asthmatic response after cat hair inhalation. These subjects may be invited to participate in a planned future study investigating novel asthma treatments.

NCT ID: NCT03768154 Active, not recruiting - Critical Illness Clinical Trials

Prone Positioning and Spontaneous Breathing

PROSE
Start date: March 1, 2019
Phase: Phase 1
Study type: Interventional

Spontaneous breathing during mechanical ventilation has been recommended in patients with ARDS and is currently used. in part because oxygenation is better and there is a lower risk of diaphragm dysfunction due to disuse. The other approach to minimizing lung injury from spontaneous effort is the use of neuromuscular blockade; an early and short term (48 hours) of neuromuscular blockade in patients with severe ARDS has been shown to decrease inflammation and to improve survival. The investigators propose a pilot study to test the feasibility and the physiological effects of allowing spontaneous breathing in the prone position in patients with ARDS.

NCT ID: NCT03747380 Completed - Lung Cancer Clinical Trials

Pre-operative Inspiratory Muscle Training Program to Prevent Pulmonary Complications After Thoracic Surgery

CT0076
Start date: January 7, 2019
Phase: N/A
Study type: Interventional

Postoperative pulmonary complications are the most common complications after thoracic surgery. In the literature, pulmonary complications after thoracic surgery are present in more than 37.5% of patients. No study investigates the impact of preoperative inspiratory muscle exercises program on pulmonary complications after thoracic surgery.

NCT ID: NCT03739879 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Effectivity of Inspiratory Muscle Trainer in the Chronic Obstructive Pulmonary Disease Rehabilitation Program

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

This study aimed to reveal the role of inspiratory muscles exercise using Inspiratory Muscle Trainer (IMT), which is a form of weight training. The pre- and post study of this experiment were conducted in chronic obstructive pulmonary disease (COPD) outpatient clinic during the period of September 2017 until April 2018. Patients were recruited by consecutive sampling. Inclusion criteria were stable COPD patient with The Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria A-D, who has never received prior exercise for pulmonary rehabilitation, and willing to participate in the study. The exclusion criteria included any problem with extremities and cardiovascular disease. Patients underwent an interview about their medical history, tested spirometry using CareFusion®, and the inspiratory muscle strength was assessed using Micro RPM CareFusion®. The St George Respiratory Questionnaire (SGRQ) was used to assess the health status and the 6-Minute Walking Test (6MWT) was conducted to assess functional capacity. Subject exercised using inspiratory muscle trainer (Philips Respironic®) for eight weeks.

NCT ID: NCT03737890 Completed - Clinical trials for Pulmonary Function in Frail Elderly

Hold Relax Pectoral Stretch vs Inspiratory Muscle Training

Start date: October 2, 2018
Phase: N/A
Study type: Interventional

Frailty is a clinical syndrome that alters the structure and function of respiratory system which causes stiffness of thoracic cage and reduces the chest wall compliance in addition of respiratory muscle weakness that can lead to the reduction of pulmonary function. The aim of this study was to compare the effect of inspiratory muscle training (IMT) and hold-relax pectoral stretch on pulmonary function (FVC, FEV1 and FEV1/FVC) among frail elderly

NCT ID: NCT03728803 Completed - Clinical trials for Inspiratory Muscle Training

Inspiratory Muscle Training in Nemaline Myopathy

NEMTRAIN
Start date: October 10, 2018
Phase: N/A
Study type: Interventional

Nemaline myopathy is a rare congenital myopathy. Respiratory failure is the main cause of death in these patients. The primary objective of this study is to determine the effect of a 8-week inspiratory muscle training program on respiratory muscle function in nemaline myopathy patients. The secondary objective is to determine respiratory muscle function in nemaline myopathy patients and its correlation with clinical severity and general neuromuscular function. The nemaline myopathy patients will be included in the first phase for a clinical characterization. From this phase patients will be selected for the second phase, which is a controlled before-after trial of inspiratory muscle training. The primary outcome is the change in maximal inspiratory pressure (MIP) after active inspiratory muscle training

NCT ID: NCT03728530 Completed - Healthy Smokers Clinical Trials

Effect Of Deep Breathing Exercises In Smokers

Start date: October 3, 2016
Phase: N/A
Study type: Interventional

To determine the effect of deep breathing exercises on lung function in healthy smokers.

NCT ID: NCT03723044 Recruiting - No Conditions Clinical Trials

Multistability: Perception is Inspired by Noise

MUSPIN-B
Start date: June 5, 2020
Phase: N/A
Study type: Interventional

Some stimuli, such as sinusoidal networks in motion, or the best known, Necker's cube, are simple visual stimulations generating interpretations of unstable and oscillatory shapes or movements, mutually exclusive. Currently, the explanatory models of these perception phenomena are based on adaptation and learning mechanisms as well as the importance of noise in the perceptual and decision-making system. Often noise is a harmful component, but it can also be a facilitator in perceptual systems: the investigator's eye is always in motion, it is the micro-movements during eye fixation (phase of eye stability). In particular, the role of micro-eye movements has been identified in perceptual systems, and it will be necessary here to relate these micro-movements to the perceptive tilts facing multisable stimuli. However, how to access the perceptive states is a real question, since it has been shown that the participant's transfer of his perceptual state by means of a motor response can alter the very state of the percept. This is why the EEG activity will be analyzed to learn to discriminate the different percepts over time, without disruption of the participant's perceptual exploration endogenous activity.

NCT ID: NCT03718858 Recruiting - Clinical trials for Obstructive Sleep Apnea

The Impact of Interscalene Block on Sleep Disordered Breathing

OSA-ISB
Start date: July 23, 2021
Phase: N/A
Study type: Interventional

This is a randomized controlled trial evaluating the impact of interscalene block on worsening of upper airway collapse in sleep disordered breathing for patients undergoing ambulatory shoulder surgery.

NCT ID: NCT03697122 Completed - Hypothermia Clinical Trials

Heated Humidified Breathing Circuit Rewarming in Hypothermic Post Cardiopulmonary Bypass Patients.

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

Hypothermia on admission to the intensive care unit (ICU) following cardiopulmonary bypass (CPB) is common. The investigators propose that rewarming hypothermic (≤ 35 C) patients admitted to the intensive care unit following procedures using CPB with heated humidified breathing circuits (HHBC) in addition to conventional forced air warming blankets will shorten time to normothermia. Secondarily it may shorten time to extubation, improve coagulopathy, and metabolic derangements seen with hypothermia.