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Respiratory Aspiration clinical trials

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NCT ID: NCT03975166 Completed - Bioequivalence Clinical Trials

A Bioequivalence Study Between Fluticasone Propionate 100 mcg and Salmeterol Xinafoate 50 mcg Inhalation Powder/Respirent Pharmaceuticals vs. ADVAIR DISKUS® 100/50 Inhalation Powder/GSK in Healthy Volunteers

Start date: May 21, 2019
Phase: Phase 1
Study type: Interventional

Bioequivalence study between two inhaler products of fixed dose combination of fluticasone propionate and salmeterol xinafoate inhalation powder

NCT ID: NCT03971396 Completed - Chest Physiotherapy Clinical Trials

The Chest Physiotherapy and Breathing Exercises Management of Patients Following Open Heart Surgery: a National Survey of Practice in Turkey.

Start date: April 30, 2019
Phase:
Study type: Observational

Chest physiotherapy and breathing exercises are an important non-pharmacological treatment modality in order to prevent and minimize postoperative respiratory complications in patients undergoing open heart surgery. Different respiratory techniques are used after cardiac surgery, but there is no opinion about which technique or exercise is effective. The purpose of this study, practical application of chest physiotherapy to patients who have had open heart surgery in Turkey and to identify methods of breathing exercises.

NCT ID: NCT03936348 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Effects of an Exercise Rehabilitation Programme With a Nasal Inspiratory Restriction Device in COPD Patients

EPOC_2_0
Start date: January 15, 2016
Phase: N/A
Study type: Interventional

This study evaluates the effects of a nasal restriction device for inspiratory muscle training (FeelBreathe) after 8 weeks of exercise intervention on exercise capacity, quality of life, dyspnea and inspitarotory muscle strength in patients with stable COPD. Participants were divided in three groups: 1) exercise intervention using the Feelbreathe® device (FB group), 2) exercise intervention with oronasal breathing without FB (ONB group) and 3) no participation in the exercise intervention as control group (CG).

NCT ID: NCT03929328 Recruiting - Clinical trials for Mechanical Ventilation

Effect of High Flow Oxygen Therapy in Spontaneous Breathing Trial on Weaning in Mechanical Ventilated Patients

HOST
Start date: June 17, 2019
Phase: N/A
Study type: Interventional

This clinical trial is aimed to show a spontaneous breathing trial using high flow oxygen therapy may lower weaning failure rate and reintubation rate than using T-piece.

NCT ID: NCT03927547 Completed - Sleep Apnea Clinical Trials

Sleep Disordered Breathing and Cardiopulmonary Disease in Peruvian Highlanders

Start date: September 29, 2019
Phase: N/A
Study type: Interventional

Overall objective: To understand the feasibility of performing a randomized trial using a simple, minimally-invasive postural therapy approach to improve sleep disordered breathing (SDB).

NCT ID: NCT03923153 Completed - Angina, Stable Clinical Trials

Effectiveness of Inspiratory Muscle Training in Patient With Stable Angina

Start date: April 15, 2019
Phase: N/A
Study type: Interventional

Stable angina is a cardiac pathology that adversely affects the quality of life of the patient, which develops as a result of narrowing of the coronary vessels developing in atherosclerotic ground and / or impaired oxygen supply-need balance. Studies widely investigated the effects of exercise training in patients with stable angina. No study investigated the effects of inspiratory muscle training in patients with stable angina.Investigators aimed to investigate the effects of inspiratory muscle training on aerobic exercise capacity, quality of life, depression, peripheral and respiratory (MIP, MEP) muscle strength, pulmonary function, dyspnea, fatigue in stable angina patients.

NCT ID: NCT03908658 Recruiting - Weaning Outcome Clinical Trials

Inspiratory Muscle Training and Nasal High Flow in Difficult Weaning

Start date: March 20, 2019
Phase: N/A
Study type: Interventional

The purpose of the present study is to investigate the effectiveness of inspiratory muscle training and nasal high flow oxygen in patients with difficult weaning and high-risk for re-intubation. The hypothesis of the study is that starting inspiratory muscle training once patients are awake and co-operative along with the application of nasal high flow oxygen immediately after extubation will have a beneficial effect in preventive re-intubation in these high-risk patients.

NCT ID: NCT03880630 Completed - Clinical trials for Chronic Respiratory Disease

Inspiratory Muscle Activation Pattern Analysis in Assisting Precision in Inspiratory Muscle Training in Patients With Chronic Respiratory Disease

Start date: October 6, 2020
Phase: N/A
Study type: Interventional

Background & Objective: Inspiratory muscle training (IMT) is known to improve strength and endurance of inspiratory muscles. However, clinical beneficial effects of IMT for patients with chronic respiratory disease remain inconclusive. The purposes of the study are to investigate in patients with chronic respiratory disease: (Year 1) main (diaphragm) and accessory inspiratory muscle (sternocleidomastoid muscle) activation pattern during various IMT loading using group-based trajectory modeling (GBTM); and (Year 2) effectiveness of individualized IMT program (based on results of Year 1) on clinical outcomes. Methods: (Year 1) Patients with chronic respiratory disease with inspiratory muscle weakness will be recruited for the study. Patients will perform 3 inspiratory loading tests (15%, 30%, and 50% of maximum inspiratory pressures) on 3 separate days with the sequence will be randomized. Surface electromyography (EMG) of diaphragm and sternocleidomastoid muscle will be used to use inspiratory muscle activation during various conditions. Other outcomes include maximum inspiratory pressure, and functional exercise capacity will be measured. Inspiratory muscle activation will be used for GBTM analysis. Patient will then be trained with individualized IMT program based on the GBTM analysis input form results of Year 1.

NCT ID: NCT03873298 Recruiting - COPD Clinical Trials

Inhaled NO in IPF and COPD During 6 Minute Walk Test

Start date: March 4, 2019
Phase: Phase 2
Study type: Interventional

Our objective is to evaluate the influence of inhaled NO on the saturation and exercise capacity of patients with COPD and IPF. each participant will undergo two six minute walk tests, one with inhaled NO and the other with placebo.

NCT ID: NCT03858244 Active, not recruiting - Clinical trials for Obstructive Sleep Apnea

Idiopathic Scoliosis Progression and Sleep-disordered Breathing in Children

Start date: February 18, 2019
Phase:
Study type: Observational

This study aimed to investigate the prevalence and clinical significance of sleep-disordered breathing (SDB) in children with mild-moderate idiopathic scoliosis (IS).