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Renal Insufficiency clinical trials

View clinical trials related to Renal Insufficiency.

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NCT ID: NCT01323075 Completed - Diabetes Clinical Trials

Pharmacodynamic Comparison of Truncal Blocks in Patients With or Without Metabolic Disease (Kidney Failure, Diabetes)

Start date: May 2011
Phase: N/A
Study type: Observational

The primary objective is to demonstrate a longer period of neurologic recovery from a sensory block assessed in each test group versus the group without metabolic disease.

NCT ID: NCT01322347 Completed - Clinical trials for Renal Failure Chronic Requiring Hemodialysis

Continuous Soluble Ferric Pyrophosphate (SFP) Iron Delivery Via Dialysate in Hemodialysis Patients (CRUISE 2)

Start date: April 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to confirm the safety and efficacy of Soluble Ferric Pyrophosphate (SFP) dialysate solution in maintaining iron delivery for erythropoiesis in anemic adult patients with chronic kidney disease (CKD) receiving hemodialysis. Efficacy will be measured primarily by the change from baseline in hemoglobin (Hgb).

NCT ID: NCT01320202 Completed - Clinical trials for Renal Failure Chronic Requiring Hemodialysis

Continuous Soluble Ferric Pyrophosphate (SFP) Iron Delivery Via Dialysate in Hemodialysis Patients

CRUISE 1
Start date: March 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to confirm the safety and efficacy of Soluble Ferric Pyrophosphate (SFP) dialysate solution in maintaining iron delivery for erythropoiesis in anemic adult patients with chronic kidney disease (CKD) receiving hemodialysis. Efficacy will be measured primarily by the change from baseline in hemoglobin (Hgb).

NCT ID: NCT01319266 Completed - Renal Impairment Clinical Trials

A Study to Assess the Pharmacokinetics of the Hydrocodone Extended-Release Tablet (CEP-33237) in Subjects With Normal Renal Function and Subjects With Varying Degrees of Renal Impairment

Start date: March 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the effect of varying degrees of renal impairment (mild, moderate, severe and end stage renal disease) compared with subjects with normal renal function on the pharmacokinetics of the hydrocodone bitartrate extended-release tablet.

NCT ID: NCT01318798 Completed - Acute Renal Failure Clinical Trials

Development and Validation of an Enhanced Prediction Score for Postoperative Acute Renal Failure After Liver Resection

Start date: January 2010
Phase: N/A
Study type: Observational

Post-operative acute renal failure is a severe post-operative complication and is associated with high mortality. The enhanced prediction score, including pre-as well as intra-operative predictors accurately predicted ARF following hepatic surgery. This prediction score allows early identification of patients at high risk of ARF and may support decision-making for protective kidney treatment.

NCT ID: NCT01316055 Completed - Renal Insufficiency Clinical Trials

Pharmacokinetics (PK) of Dalfampridine-ER 7.5 mg BID in Healthy Volunteers and Subjects With Mild or Moderate Renal Impairment

Start date: January 2011
Phase: Phase 1
Study type: Interventional

The steady-state pharmacokinetics of Dalfampridine-ER (extended release) 7.5 mg (milligram) tablets in healthy adult volunteers and those with mild and moderate renal impairment, and examine between group comparisons.

NCT ID: NCT01315314 Completed - Clinical trials for Kidney Failure, Chronic

Effect of Glucose Degradation Products (GDP) on Endothelial Dysfunction

Start date: October 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effects of neutral pH and low glucose degradation product (GDP)-containing peritoneal dialysis fluid (PDF) on systemic inflammation and endothelial dysfunction markers in incident PD patients.

NCT ID: NCT01314391 Completed - Kidney Cancer Clinical Trials

Biomarkers in Blood and Tumor Tissue Samples From Patients With Wilms Tumor

Start date: August 2011
Phase: N/A
Study type: Observational

RATIONALE: Studying samples of blood and tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research study is studying biomarkers in blood and tumor tissue samples from patients with Wilms tumor.

NCT ID: NCT01312727 Completed - Gout Clinical Trials

Hereditary Tubulointerstitial Nephritis

NTIH
Start date: November 2010
Phase: N/A
Study type: Interventional

The aim of this study is to identify families with hereditary chronic tubulointerstitial renal diseases , characterize the phenotype and screen for mutations in known genesis (UMOD, REN, TCF2, NPHP1). Genome wide analysis will be performed in families without mutations identified.

NCT ID: NCT01309438 Completed - Healthy Clinical Trials

A Study of Erythromycin and Rivaroxaban in Study Participants With Normal and Reduced Kidney Function

Start date: February 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the pharmacokinetics and pharmacodynamics of rivaroxaban when administered with erythromycin to study participants with mild or moderate renal impairment compared to the pharmacokinetics and pharmacodynamics of rivaroxaban administered to study participants with normal renal function.