Prevalence of Renal Artery Stenosis in Patients Referred for Cardiac Catheterization

Renal Artery Stenosis Clinical Trial

— RAS  

Official title:

Prevalence of Renal Artery Stenosis in Patients Refered for Cardiac Catheterization to Heart Center Hospital in July-September 2008

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00885768
• Other study ID #: RAS001
• Status: Completed
• Phase: Phase 3
• First received: July 11, 2008
• Last updated: May 11, 2011
• Start date: July 2008
• Est. completion date: April 2009

Study information

• Verified date: April 2009
• Source: Imam Khomeini Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Iran: Ethics Committee
• Study type: Observational

Clinical Trial Summary

All patients referred for coronary angiography will simultaneously be evaluated for renal artery stenosis and then stenosis more than 50% will be analyzed according to clinical conditions, risk factors and lab data.

Description:

Renal Artery Stenosis (RAS) is a common finding in patients with generalized atherosclerosis. It is the cause of 15-20% of end stage renal disease in elderly patients. The prevalence of asymptomatic RAS in general population is unknown but it estimated to be 18% in 7th decade and more than 50% in the 8th. It is critical to find and manage the RAS before it's symptoms appear. The Gold standard for diagnosis of atherosclerotic arterial stenosis is angiography. In this study we will evaluate the prevalence, severity, location and related factors to renal artery stenosis in patients whom referred for coronary angiography in period of July-September in one of the most referral heart center in Iran, "The Tehran heart center" which is doing more than 50 coronary angiography daily.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 146
• Est. completion date: April 2009
• Est. primary completion date: September 2008
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• age more than 18 years

Exclusion Criteria:

• contraindication to contrast use

• not signing consent

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

• Constriction, Pathologic
• Renal Artery Obstruction
• Renal Artery Stenosis

Intervention

Procedure:
• angiography
all patients undergoing coronary angiography with VISIPAQUE and if they had coronary stenosis then renal artery angiography will be done. the dose of contrast will be chosen according to renal function and clinical conditions which will be varied from 75 to 300 ml.

Locations

Country	Name	City	State
Iran, Islamic Republic of	Tehran Heart Center	Tehran

Sponsors (2)

Lead Sponsor	Collaborator
Imam Khomeini Hospital	Tehran Heart Center

Country where clinical trial is conducted

Iran, Islamic Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Prevalence of Renal Artery Stenosis (RAS)		2 months	Yes
Primary	The Number of Patients With Renal Artery Stenosis	the prevalence of renal artery stenosis in patients with coronary artery disease	3months	Yes