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Recurrence clinical trials

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NCT ID: NCT04409496 Completed - Smoking Cessation Clinical Trials

Chat-based Support for Preventing Smoking Relapse

Start date: June 2, 2020
Phase: N/A
Study type: Interventional

This pilot trial aims to evaluate the effectiveness of chat-based instant messaging support in preventing smoking relapse in recent tobacco abstainers.

NCT ID: NCT04409314 Completed - Clinical trials for Recurrent Plasma Cell Myeloma

Hypoxia-Specific Imaging to Predict Outcomes of Chimeric Antigen Receptor T-cell Therapy

Start date: April 16, 2020
Phase:
Study type: Observational

This study evaluates whether tumors present in patients with cancer who are planned to get CAR T-cells have low amounts of oxygen (hypoxia). PET scans may be used to check the amounts of oxygen within areas of cancer with a special radioactive tracer called FAZA that specifically looks for areas of low oxygen. This study is being done to help researchers determine how the amount of oxygen within areas of cancer affect how well CAR T-cells kill cancer cells.

NCT ID: NCT04406974 Recruiting - Clinical trials for Colorectal Neoplasms

Locally Advanced Colorectal Cancer and Local Recurrences in Västra Götaland

Start date: January 1, 2018
Phase:
Study type: Observational

The aim of this study is to review the treatment strategies of locally advanced colorectal cancer and locally recurrent rectal cancer in Västra Götaland during 1995-2016. The aim is to evaluate time trends and outcome both related to morbidity and cancer specific survival, we will also evaluate the results after advanced reconstruction. The study will identify the population using the Swedish ColoRectal Cancer Registry and then the individual patient charts will be reviewed. The data will be collected in a clinical record form covering demography (age, sex, co-morbidity, BMI and diagnoses) as well as treatments strategy, surgical procedures, re-operations, complications, readmissions, hospital stay, stoma formation etc.

NCT ID: NCT04406272 Active, not recruiting - Glioblastoma Clinical Trials

VB-111 in Surgically Accessible Recurrent/Progressive GBM

Start date: August 1, 2020
Phase: Phase 2
Study type: Interventional

This research study is studying a new viral cancer therapy, ofranergene obadenovec (VB-111), for recurrent or progressive glioblastoma (GBM), a brain tumor that is growing or progressing despite earlier treatment.

NCT ID: NCT04405622 Active, not recruiting - Clinical trials for Nasopharyngeal Carcinoma

Toripalimab and Gemcitabine in Recurrent or Metastatic Nasopharyngeal Carcinoma.

Start date: May 30, 2020
Phase: Phase 2
Study type: Interventional

This is an open-label, single center, pilot trial to evaluate the safety and efficacy of toripalimab and gemcitabine in patients with recurrent or metastatic nasopharyngeal carcinoma.

NCT ID: NCT04404777 Recruiting - Rectal Neoplasms Clinical Trials

Local Recurrence Due to Rectal Cancer in Sweden

LERIS
Start date: July 1, 2022
Phase:
Study type: Observational [Patient Registry]

The aim of this retrospective national registry study is to validate the reporting of local recurrence in the registry. Another aim is to identify preoperative risk factors for local recurrence. This can in turn indicate the need for a more intense follow-up. The treatment of local recurrence, including the impact of the multidisciplinary team conference (MDT) and the surgical procedure and the referral pathways of local recurrences will also be determined. We aim to evaluate treatment outcome after local recurrence for patients operated or treated between 2007-2018.

NCT ID: NCT04404491 Not yet recruiting - Clinical trials for Esophageal Malignant Neoplasm, Local Recurrence

Clinical Control Study of Immunotherapy and Concurrent Chemoradiotherapy in Patients With Esophageal Cancer Recurrence

Start date: June 1, 2020
Phase: Phase 3
Study type: Interventional

Esophageal cancer is still a serious threat to human life and health. China in particular. Relapse and metastasis are important causes of treatment failure. Immunotherapy is a new treatment method, which can be used in combination with chemotherapy to improve the therapeutic effect. However, the role of immunotherapy combined with chemoradiotherapy in concurrent chemoradiotherapy of recurrent esophageal cancer has not been clearly studied. Our team will study it in detail. The purpose of this study was to compare and analyze the effect of Camrelizumab in concurrent chemoradiotherapy of locally recurrent esophageal cancer.

NCT ID: NCT04396886 Completed - Metastatic Cancer Clinical Trials

Bintrafusp Alfa in Previously Treated Patients With R/M Non-keratinizing NPC

Start date: February 27, 2020
Phase: Phase 2
Study type: Interventional

This would be a phase II prospective single arm mono-institutional study conducted in Queen Mary Hospital (Hong Kong) assessing the efficacy and safety of bintrafusp alfa in previously treated patients with recurrent and metastatic (R/M) non-keratinizing nasopharyngeal carcinoma (NPC).

NCT ID: NCT04395534 Completed - Colon Cancer Clinical Trials

Non-microradical Resection Margin as a Predictor for Recurrence After Complete Mesocolic Excision

Start date: June 1, 2008
Phase:
Study type: Observational

The study aim to investigate the value of the current definition of microradical resection margin in colon cancer. Is the distance from tumor tissue to resection margin and the site of any clinically prognostic importance if complete mesocolic excision has been performed.

NCT ID: NCT04395079 Active, not recruiting - Clinical trials for Recurrent Malignant Female Reproductive System Neoplasm

Brachytherapy With Durvalumab or Tremelimumab for the Treatment of Patients With Platinum-Resistant, Refractory, Recurrent, or Metastatic Gynecological Malignancies

Start date: August 7, 2020
Phase: Phase 2
Study type: Interventional

This phase II trial studies the side effects and how well brachytherapy with durvalumab or tremelimumab work for the treatment of gynecological malignancies that is resistant to platinum therapy (platinum-resistant), does not respond to treatment (refractory), has come back (recurrent), or has spread to other places in body (metastatic). Brachytherapy, also known as internal radiation therapy, uses radioactive material placed directly into or near a tumor to kill tumor cells. Immunotherapy with monoclonal antibodies, such as durvalumab and tremelimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial is being done to see whether brachytherapy with durvalumab or tremelimumab works better in treating patients with gynecological malignancies.