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Comparison of Remimazolam With Flumazenil vs. Propofol During RFCA for Atrial Fibrillation

Recovery Clinical Trial

Official title:
Comparison of Remimazolam With Flumazenil vs. Propofol TIVA During RFCA for Atrial Fibrillation

Clinical Trial Summary

This prospective randomized trial aims to compare recovery time from discontinuation of remimazolam followed by flumazenil administration vs. propofol total intravenous anesthesia as the main general anesthetics during radiofrequency catheter ablation treatment of atrial fibrillation.

Clinical Trial Description

Adult patients with atrial fibrillation undergoing radiofrequency catheter ablation under general anesthesia are randomized to receive either remimazolam with flumazenil or propofol total intravenous anesthesia as the main anesthetics. After completion of radiofrequency ablation, each anesthetic is discontinued. The primary outcome of the study is comparison of the time to the first eye opening responding to doctor's command from the discontinuation of each drug between the groups. Secondary outcomes includes the time to removal of supraglottic laryngeal mask airway device from discontinuation of each drug, incidence of three consecutive hypotension (systolic blood pressure under 80 mmHg) recordings at 2.5 min-intervals, and intraprocedural vasoactive-inotropic score. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05397886
Study type Interventional
Source Seoul National University Hospital
Contact
Status Completed
Phase N/A
Start date August 2, 2022
Completion date April 25, 2023
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