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Radiofrequency Ablation clinical trials

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NCT ID: NCT04513119 Recruiting - Clinical trials for Radiofrequency Ablation

The Short-term Efficacy of Novel NTDP-RFA in the Treatment of Small HCC With Cirrhosis.

Start date: January 1, 2017
Phase:
Study type: Observational

To evaluate the short-term efficacy of novel no-touch combined directional perfusion radiofrequency ablation in the treatment of small hepatocellular carcinoma with cirrhosis.

NCT ID: NCT04471272 Recruiting - Clinical trials for Carcinoma, Hepatocellular

RFA Using Gradual RF Energy Delivery Mode With Octopus Electrodes

Start date: January 6, 2020
Phase: N/A
Study type: Interventional

The investigators intend to perform RFA therapy on HCC less than 4 cm in size using octopus electrode, double alternating unipolar high-frequency transmission mode and gradual high-frequency energy loading mode, and to find out the therapeutic results. The primary evaluation variable is the ideal technical success rate for securing a safety margin of 5 mm or more around the tumor on the CT obtained immediately after the procedure, and the secondary evaluation variable is the volume of the cauterization lesion per unit time measured on the CT obtained immediately after the procedure, The local tumor recurrence rate, survival rate and disease-free survival rate of 12 months after the procedure, the presence or absence of multiple recurrences within the same segment, the actual procedure time, and the incidence of complications associated with the procedure are examined. The performance of RFA therapy of HCC using the Octopus electrode and gradual high-frequency energy transfer mode is compared with that of the existing Octopus electrode and RFA therapy using the basic maximum high-frequency energy transfer mode using historic cohort.

NCT ID: NCT04420013 Not yet recruiting - Colorectal Cancer Clinical Trials

Colorectal Cancer Immunomonitoring Combined With Radiofrequency ablatIon

ColIBRI
Start date: September 2020
Phase:
Study type: Observational

The primary objective of the study aims to compare soluble CD154 (CD40L) levels before and after radiofrequency ablation (RFA) in patients with colorectal cancer (CRC) liver metastases. The secondary objectives aims: - to compare soluble CD154 (sCD40-L) levels before and after treatment by RFA or surgery alone in patients with CRC liver metastases; - to study the feasibility and reliability of soluble CD154 (sCD40-L) levels to detect and quantify the induction of immun response in CRC liver metastases patients after RFA; - to study the impact of surgery on plasma soluble CD154 levels; - to study association between CD154 expression level before and after RFA in CRC liver metastases patients and relapses rate at 1 year.

NCT ID: NCT04417010 Not yet recruiting - Colorectal Cancer Clinical Trials

To Identify KRAS Gene and Safe Margin in Association With Outcome in Colorectal Liver Metastases Following Ultrasound-guided Radiofrequency Ablation

Start date: June 1, 2020
Phase:
Study type: Observational

To investigate the clinical effect of radiofrequency ablation on colorectal cancer liver metastases with different KRAS gene status

NCT ID: NCT04331184 Recruiting - Clinical trials for Carcinoma, Hepatocellular

RFA Using Combined Bipolar and Monopolar Energy Deliver With Twin Cooled-Wet Electrodes

Start date: January 28, 2020
Phase: N/A
Study type: Interventional

In this study, a dual / Twin Cooled-wet electrode was used to perform RFA therapy on residual tumors after transarterial chemo-embolization and to find out the therapeutic results. The primary endpoint is the 12-month local recurrence rate, and the secondary endpoint is the survival rate, disease-free survival rate, actual procedure time, complications associated with the procedure, and the technical success rate for securing a safety margin of 3 mm or more around the tumor.

NCT ID: NCT04152954 Completed - Neck Pain Clinical Trials

Comparison of a Multi-tined Cannula Versus a Conventional Cannula for Cervical Medial Branch Radiofrequency Ablation in Chronic Neck Pain

Start date: December 4, 2019
Phase: N/A
Study type: Interventional

Chronic neck pain is a common disorder for spine specialists. Radiofrequency ablation of medial branches has been proven effective in selected patients for relieving pain. A newer radiofrequency ablation cannula has been developed (multi-tined), allowing perpendicular access. It is proposed as an alternative to the more technically challenging traditional approach. This study aims to compared the technical and clinical aspects of both techniques.

NCT ID: NCT04150744 Recruiting - Immunosuppression Clinical Trials

RFA Plus Carrizumab vs Carrizumab Alone for HCC

Start date: August 1, 2020
Phase: Phase 2
Study type: Interventional

The study aims to find whether patients with advanced HCC can get more benefits from RFA +PD-1 immunosuppressant (carrizumab) compared with carrizumab alone, considering with the result of PFS.

NCT ID: NCT03574831 Recruiting - GERD Clinical Trials

the Efficency and Safety of Stretta in GERD

Start date: January 2, 2016
Phase:
Study type: Observational

This study evaluated the efficency and safety of the endoscopic radiofrequency procedure(Stretta) in adult gastroesophageal patients.

NCT ID: NCT03375281 Completed - Clinical trials for Hepatocellular Carcinoma

Radiofrequency Ablation Using Octopus Electrodes for Small Hepatocellular Carcinoma With No-touch Technique

Start date: November 20, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate clinical outcome of RFA for small single nodular HCC using no touch technique with separable clustered electrode (Octopus) in a prospective multicenter manner Participating center: Seoul national university hospital, Asan medical center, Samsung medical center, Kunkuk university hospital, St. mary's Seoul hospital

NCT ID: NCT03247413 Terminated - Clinical trials for Radiofrequency Ablation

Post-lesion Administration of Dexamethasone to Prevent the Development of Neuritis After Radiofrequency Ablation

Start date: September 1, 2019
Phase: Phase 4
Study type: Interventional

Chronic neck and back pain has become one of the leading causes of disability and loss of productivity. For many patients with facet or sacroiliac joint mediated pain who have responded to diagnostic nerve blocks, radiofrequency ablation of the nerves innervating the joints can provide long term relief. Radiofrequency ablation (RFA) is a relatively safe procedure with minimal risk of adverse events. However, with any procedure involving damage to the peripheral nervous system, there is risk of post-procedure neuropathic pain. The investigators will test the hypothesis that dexamethasone injection delivered at the time of lesion effectively prevents the development of post-ablation neuritis through a placebo-controlled, double-blind, randomized trial in patients undergoing cervical, thoracic, lumbar, and sacroiliac joint radiofrequency denervations