Quality of Life Clinical Trial
— RENALTXOfficial title:
Physiological and Molecular Effects of Exercise Training in Kidney Transplantation Recipients
Verified date | January 2024 |
Source | Catholic University of Brasília |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The goal of this clinical trial is to investigate the physiological and molecular effects of exercise training in transplant recipients. The main questions it aims to answer are: 1. Can exercise training improve physical fitness and muscle strength in transplant recipients? 2. Can exercise training modulate inflammatory profile, hormones, lipid profile, and exercise-induced molecules in transplant recipients? 3. Can exercise training improve blood pressure and endothelial health in transplant patients? Participants will be invited to an exercise training program 6-month after their transplant surgery. Body composition, physical assessment, and blood draw will be assessed at baseline and 12-weeks after exercise or control regimen. Researchers will compare exercise group vs. routine care group to see if exercise training impact the health-related outcomes of this population.
Status | Completed |
Enrollment | 345 |
Est. completion date | December 5, 2023 |
Est. primary completion date | November 3, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 60 Years |
Eligibility | Inclusion Criteria: - Medical Authorization: - Stable Health Status - Medication Consistency - No History of Severe Cardiovascular Events - No Major Orthopedic Issues - Non-Smokers or Consistent Smoking Habits - Ability to Comply with Study Protocols Exclusion Criteria: - Inability to Comply - Cognitive disorders - Unwillingness to Continue - Unstable Health Conditions - Physical limitations during the protocol |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Hugo de Luca Correa | Catholic University of Brasília, Federal University of São Paulo |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Functional performance | 6-minute walking test | Baseline, after 12-weeks and at the end of the protocol | |
Primary | Muscle strength | One Repetition Maximum Test | Baseline, after 12-weeks and at the end of the protocol | |
Primary | Isometric muscle strength | Handgrip strength | Baseline, after 12-weeks and at the end of the protocol | |
Primary | Physical fitness | Ergospirometric Test | Baseline, after 12-weeks and at the end of the protocol | |
Secondary | Inflammatory profile | Interleukin 6, interleukin 10, and tumor necrosis factor | Baseline, after 12-weeks and at the end of the protocol | |
Secondary | Urea-to-creatinine ratio | Urea and creatinine will be combined to report urea-to-creatinine ratio | Baseline, after 12-weeks and at the end of the protocol | |
Secondary | Blood glucose | Fasting blood glucose levels | Baseline, after 12-weeks and at the end of the protocol | |
Secondary | Hormones | Irisin, Klotho, and adiponectin | Baseline, after 12-weeks and at the end of the protocol | |
Secondary | Graft rejection | Number of patients that rejected their graft | Through study completion, an average of 5 years |
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT05559255 -
Changes in Pain, Spasticity, and Quality of Life After Use of Counterstrain Treatment in Individuals With SCI
|
N/A | |
Completed |
NCT06238557 -
Prospective Evaluation of Psychological Consequences and Impact on Long-term Quality of Life
|
||
Recruiting |
NCT05563805 -
Exploring Virtual Reality Adventure Training Exergaming
|
N/A | |
Completed |
NCT05472935 -
Asynchronous Mindfulness Based Stress Reduction to Reduce Burnout in Licensed Clinical Social Workers
|
N/A | |
Recruiting |
NCT04444544 -
Quality of Life and High-Risk Abdominal Cancer Surgery
|
||
Completed |
NCT04281953 -
Impact on Quality of Life of Long-term Ototoxicity in Cancer Survivors
|
||
Recruiting |
NCT05546931 -
Mobile Health Program for Rural Hypertension
|
N/A | |
Active, not recruiting |
NCT04746664 -
Effects of Nutrition Counselling on Old Age People's Nutritional Status and Quality of Life in Bahir Dar City, North West Ethiopia
|
N/A | |
Completed |
NCT05387174 -
Nursing Intervention in Two Risk Factors of the Metabolic Syndrome and Quality of Life in the Climacteric Period
|
N/A | |
Recruiting |
NCT04142827 -
The Effect of Long Term Therapy With High Flow Humidification Compared to Usual Care in Patients With Bronchiectasis (BX)
|
N/A | |
Active, not recruiting |
NCT05903638 -
A Pilot RCT: the Impact of a Virtual MBSR Course on Women With Primary Infertility
|
N/A | |
Completed |
NCT05538455 -
Investigating ProCare4Life Impact on Quality of Life of Elderly Subjects With Neurodegenerative Diseases
|
N/A | |
Completed |
NCT03813420 -
Sleep Quality of Physiotherapy Students Quality of Life and Physical Activity Level
|
N/A | |
Recruiting |
NCT05550545 -
Infant RSV Infections and Health-related Quality of Life of Families
|
||
Completed |
NCT05346588 -
THRIVE Feasibility Trial
|
Phase 3 | |
Recruiting |
NCT05233020 -
Robotic Versus Hybrid Assisted Ventral Hernia Repair
|
N/A | |
Terminated |
NCT03304184 -
The Role of Biodentine in Class V Dental Lesions on Oral Health Related Quality of Life
|
Phase 3 | |
Completed |
NCT05063305 -
Probiotics, Immunity, Stress, and QofL
|
N/A | |
Recruiting |
NCT05380856 -
Sacral Neuromodulation for Neurogenic Lower Urinary Tract, Bowel and Sexual Dysfunction
|
N/A | |
Completed |
NCT05934578 -
Lymphatic Function in Patients With Fontan Circulation: Effect of Physical Training
|
N/A |