Yoga Effects on Heart Rate Variability and Electroencephalography

Quality of Life Clinical Trial

Official title:

Effects of Yoga on Heart Rate Variability, Electroencephalography, Quality of Life and Salivary Cortisol of Healthy Adult Subjets

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01866683
• Other study ID #: 184.583
• Status: Completed
• Phase: N/A
• First received: May 23, 2013
• Last updated: June 11, 2015
• Start date: January 2013
• Est. completion date: March 2014

Study information

• Verified date: June 2015
• Source: University of Sao Paulo
• Contact: n/a
• Is FDA regulated: No
• Health authority: Brazil: National Committee of Ethics in Research
• Study type: Interventional

Clinical Trial Summary

Since yoga breathing exercises are traditionally used to tranquilize the mind, and have a well-known positive effect on the cardiovascular system, it is our hypothesis that a respiratory yoga exercise named bhastrika pranayama may have positive effects on heart rate variability, electroencephalography, quality of life and salivary cortisol (stress hormone).

Description:

The effects of yoga interventions on heart rate variability have been previously shown in our laboratory, having its efficacy in improving autonomic heart modulation of hypertensives and elderly subjets proven. However, there is a lack of data addressing the effects of such interventions on EEG patterns of health fit male subjects, as well as there are no study investigating if there is a relationship between heart autonomic modulation changes and EEG patterns. Thus, the aim of this study was to investigate the effects of 1 month respiratory yoga training on heart rate variability, EEG, salivary cortisol and quality of life of health fit male subjets.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: March 2014
• Est. primary completion date: March 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 25 Years to 45 Years

Eligibility

Inclusion Criteria:

• Young adults;

• Physically fit (engaged in physical activity at least 2-3 times a week);

• Non athletes;

• Possibility to follow protocol agenda.

Exclusion Criteria:

• Epileptic events in previous 5 years;

• Chronic allergic rhinitis, with airway occlusion;

• Oral bronchodilator usage;

• Beta blocker user;

• Any diagnosed cardiac rhythm alteration at rest;

• Cerebral dysrhythmia;

• Previous training in respiratory yoga exercises.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Supportive Care

Related Conditions & MeSH terms

• Health Behavior
• Quality of Life

Intervention

Behavioral:
• 1 month respiratory training
Bhastrika yoga respiratory training: 30 kapalabhati and 1 surya bedhana form 1 bhastrika
• 1 month waiting period
waiting or detraining period

Locations

Country	Name	City	State
Brazil	Universidade Federal do Rio Grande do Norte - UFRN	Natal	Rio Grande do Norte

Sponsors (2)

Lead Sponsor	Collaborator
University of Sao Paulo	Conselho Nacional de Desenvolvimento Científico e Tecnológico

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Changes from baseline electroencephalography measures of brain waves at 1 and 2 months	64 active electrodes electroencephalography	baseline, one month, two months	No
Secondary	frequency domain heart rate variability	R-R interval autoregressive spectral analysis	study entry, one month, two months	No
Secondary	salivary cortisol		study entry, one month, two months	No
Secondary	quality of life	quality of life will be addressed by the World Health Organization Questionaire of Quality of Life in its brief form	study entry, one month, two months	No