Mometasone Furoate Nasal Spray in Italian Children

Status Completed

Clinical Trial Summary

Clinical Trial Description

Objective Seasonal allergic rhinitis (SAR) is a common disease in childhood and characterized by type 2 inflammation, bothersome symptoms, and impaired quality of life (QoL). Intranasal corticosteroids are effective medications in managing SAR patients. In addition, mometasone furoate nasal spray (MFNS) is a well-known therapeutic option. However, the literature provided no data about its effects in European children with SAR. Thus this study addressed this unmet need. Methods MFNS was compared to isotonic saline. Both treatments were prescribed one spray per nostril, twice a day, per 3 weeks. Nasal cytology, total symptom score (TSS), visual analogic scale concerning the parental perception of symptom severity, and the Pediatric Rhinoconjunctivitis Quality of Life Questionnaire (PRQLQ) were assessed at baseline, after 7 and 21 days, and one month after discontinuation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05301647
Study type	Observational
Source	University of Campania "Luigi Vanvitelli"
Contact
Status	Completed
Phase
Start date	June 20, 2019
Completion date	October 20, 2021

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