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Quality of Life Related to Different Treatment Protocols for Post-thyroidectomy Hypoparathyroidism

Quality of Life Clinical Trial

Official title:
Comparing the Quality of Life Associated With Empiric Calcium Repletion and Parathormone (PTH) Based Calcium Repletion for Post Thyroidectomy Hypoparathyroidism

Clinical Trial Summary

This study aims to compare two different protocols commonly used in the management of post thyroidectomy hypoparathyroidism : PTH based calcium repletion and empiric repletion. The investigators aim to compare the quality of life associated with these two protocols in a randomized trial.

Clinical Trial Description

Enrolled patients will be randomized in two treatment groups. In group 1, all patients will receive calcium carbonate and calcitriol in the post-operative period, with standardized weaning. In group 2, patients will be prescribed calcium carbonate and calcitriol only if their post-operative PTH dosage is 25% or less of the pre-operative dosage, or if post-operative PTH is inferior to 15. The Short-Form 36 (SF-36) questionnaire (French canadian version) will be used to assess quality of life pre-operatively and at post-op week 1 and 4. Symptoms of hypocalcemia and adverse effects of calcium carbonate and calcitriol will be monitored at week 1 and 4. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03249012
Study type Interventional
Source CHU de Quebec-Universite Laval
Contact Jean-Philippe Vezina, MD, FRCSC
Phone 418-649-0252
Email jean-philippe.vezina@fmed.ulaval.ca
Status Recruiting
Phase N/A
Start date September 1, 2017
Completion date September 1, 2025
View Details
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