Clinical Trials Logo
  1. Home
  2. Pulp Disease, Dental
  3. NCT05633537

Clinical & Radiographic Evaluation of Zinc Oxide-Ozonated Oil as a New Primary Root Canal Filling

Root Canal Infection Clinical Trial

Official title:
Clinical and Radiographic Evaluation of Zinc Oxide-Ozonated Oil as a New Root Canal Filling Material for Primary Molars

Clinical Trial Summary

Preserving primary teeth is essential for many aspects such as the child's growth and development, esthetic, functional, psychological, and dental arch integrity aspects. a randomized blinded controlled clinical trial aimed to evaluate the clinical and radiographic success of Zinc Oxide-Ozonated Olive Oil as root canal filling materials for primary molars compared to Zinc Oxide-Olive Oil & Zinc Oxide-eugenol. 90 primary molars of 30 children aged between 4-8 years with pulpally involved primary molars, are equally divided into 3 groups which treated with Zinc Oxide-Ozonated Olive Oil , zinc oxide -olive oil and zinc oxide eugenol as obturation materials following pulpectomy procedure. The subjects were followed up clinically and radiographically at 3, 6 and 12 months.

Clinical Trial Description

Pulpectomy for primary teeth involves root canal preparation followed by obturation with a resorbable material. Zinc oxide eugenol (ZOE) is the most widely used obturating material. The main ZOE disadvantages are the difference in rate of resorption compared to the root, and limited antimicrobial activity. ZOE is formed when crude eugenol is mixed with zinc oxide. the set material easily hydrolyzes, resulting in free eugenol release which can be harmful to human soft tissues; this motivated the search for a new eugenol substitute to be combined with zinc oxide. Olive oil is a vegetable oil that comprises antioxidants, carotenoids, oleuropein, and oleocanthal, a phenolic component that significantly contributes to its antibacterial and anti-inflammatory properties. ozone in the form of ozonated olive oil, have the ability to produce nascent oxygen deep into the treated area without triggering irritation so, improved rheological characteristics, increased intracellular ATP, stimulated cellular metabolism, and expression of cytokines related to healing, particularly Transforming Growth Factor. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05633537
Study type Interventional
Source Tanta University
Contact
Status Completed
Phase N/A
Start date July 4, 2021
Completion date May 29, 2023
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT04527705 - Outcome of Endodontic Retreatment in One or Two Visits N/A
Active, not recruiting NCT06027931 - Traditional Versus Conservative Access Cavities Cleaning Ability N/A
Completed NCT03635515 - Occurrence of Post-op Pain Following Gentlewave N/A
Completed NCT03841370 - Tooth Crown Discoloration Caused by Endodontic Treatment
Completed NCT03756363 - The Effect of Solvent Usage on Post-treatment Pain N/A
Completed NCT03719404 - Irrigants on Outcome of Non Surgical Endodontic Retreatment N/A
Recruiting NCT05959629 - Erbium, Chromium: Yttrium, Scandium, Gallium, Garnet (Er,Cr:YSGG) Laser in Root Canal Disinfection N/A
Completed NCT05039502 - Releasing of Inflammatory Mediators During Retreatment of Root Canals N/A
Active, not recruiting NCT05555043 - Comparison of Clinical Outcomes Between GentleWave® and Biolase® N/A
Recruiting NCT03384004 - Effect of Apical Negative Pressure Irrigation System at Cleaning Lateral Canals and Reduction of Periapical Lesions After Endodontic Therapy N/A
Completed NCT05778227 - Comparing Different Single and Combination Chelating Agents on Sealer Penetration and Dentin Erosion. N/A
Completed NCT05476445 - Effect of Cryotherapy and LLLT on Postoperative Pain After Root Canal Treatment N/A
Enrolling by invitation NCT05714384 - Outcome of Calcium Silicate Sealer-based Obturation in Root Canal Retreatment
Completed NCT03042377 - Postoperative Pain in Single-visit and Multiple-visit Retreatment Cases Phase 4
Recruiting NCT04933955 - Evaluation of Post Operative Pain and Success Rate After Pulpotomy N/A
Completed NCT05006209 - One-visit Root Canal Treatment Using Chlorhexidine as a Final Irrigant N/A
Completed NCT05137613 - One and Two-visit Root Canal Retreatment N/A
Completed NCT04399720 - Root Canal Treatment Outcome in Patients Under Bisphosphonate Therapy
Recruiting NCT03055975 - Prevalence of Bacteria Following Endodontic Treatment N/A
Recruiting NCT04655105 - Evaluation of Post Operative Pain Following Reciprocating and Rotary Heat-treated NiTi Instrumentation of Root Canals: a Randomized Controlled Clinical Trial N/A