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Pulp Disease, Dental clinical trials

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NCT ID: NCT06380296 Not yet recruiting - Clinical trials for Pulp Disease, Dental

Outcomes of NeoMTA and NeoPUTTY Pulpotomies in Primary Molars

Start date: April 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the outcomes of different medications used for pulpotomies (baby root canal) in children. The main question it aims to answer is: • what are the long-term clinical and radiographic success of pulpotomies in baby teeth using two different medications (NeoMTA and NeoPUTTY) over a 24-month follow-up period? Healthy children aged between 3 and 10 years undergoing dental treatment under general anesthesia who have deep caries lesions approximating or reaching the nerve will be invited to participate in this study. Pulpotomies (baby root canal) will be performed by trained dentists following a protocol. Children will receive pulpotomies either with NeoMTA or NeoPUTTY, two medications indicated for the procedure. Participants will be asked to come for an appointment at 1, 6, 12 and 24 months after the procedure. Researcher will compare the clinical and radiographic performance of pulpotomies (baby root canal) done with both medications.

NCT ID: NCT06227390 Recruiting - Clinical trials for Pulp Disease, Dental

Clinical and Radiographic Outcomes of Partial Pulpotomy Procedure in Primary Molars Utilizing Different Capping Materials and Different Restorative Methods

Start date: October 15, 2023
Phase: N/A
Study type: Interventional

the goal of this clinical trial is to compare clinical and radiographic outcomes of partial pulpotomy in vital primary molars using TheraCal PT®, Biodentin® and NeoPUTTY® MTA , followed by glass ionomer restoration only or glass ionomer restoration and stainless-steel crown.

NCT ID: NCT06207253 Recruiting - Endodontic Disease Clinical Trials

The Antimicrobial Potential of Diclofenac Sodium as an Intracanal Medicament

Start date: February 2024
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this randomized clinical trial is to evaluate the capability of the material to exert bacterial reduction of diclofenac sodium versus of that calcium hydroxide paste when these materials are used as intracanal medications in permanent molar teeth with chronic apical periodontitis. The main question[s] it aims to answer are: • Will the diclofenac sodium (NSAIDs) possess antimicrobial efficacy to be used effectively as an intracanal medicament similar to that of calcium hydroxide in primary endodontic treatment? Participants will be allocated randomly into three equal groups by using computer generated randomization, according to the type of intracanal medication.

NCT ID: NCT06196515 Recruiting - Endodontic Disease Clinical Trials

Anti-bacterial Potential of Nano Calcium Hydroxide as an Intracanal Medication

Start date: January 2024
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of the study is to evaluate the anti-bacterial potential of Nano Calcium Hydroxide as an intracanal medication in primary endodontic treatment of permanent molars.

NCT ID: NCT06170775 Not yet recruiting - Clinical trials for Pulp Disease, Dental

Sodiumhexametaphosphate as Pulp Capping Material for Primary Teeth

Start date: December 20, 2023
Phase: N/A
Study type: Interventional

Sodiumhexametaphosphate will be tested as pulp capping material in comparison to MTA for primary teeth pulp therapy

NCT ID: NCT06170762 Not yet recruiting - Clinical trials for Pulp Disease, Dental

Sodiumhexametaphosphate Versus MTA as Pulp Capping Material for Immature Permanent Teeth

Start date: December 20, 2023
Phase: N/A
Study type: Interventional

Sodiumhexametaphosphate will be used as capping material for dental pulp of immature permanent teeth

NCT ID: NCT06129643 Completed - Clinical trials for Apical Periodontitis

Post-operative Pain After Laser Root Canal Treatment of Necrotic Teeth With Apical Periodontitis

Start date: January 1, 2022
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate in vivo the post operative pain after laser root canal treatment in necrotic teeth in an evidence-based clinical trial. The null hypothesis being tested is that there is no difference in post operative pain between conventional irrigation and the two types of lasers used. Thirty patients are equally divided into 3 separate groups : - Group A (Conventional): 2.5% NaOCL and 17% EDTA. - Group B(Dual): saline along with Er,Cr:YSGG laser and diode laser combination - Group C(Combined): saline along with 17% EDTA and diode laser combination Each patient is given pain scale chart Numeric Rating Scale (NRS) to record his/her pain level before any endodontic treatment. All data will be collected, tabulated, summarized, and statistically analyzed.

NCT ID: NCT06110494 Completed - Clinical trials for Apical Periodontitis

A New Clinical Use of Ferumoxytol Nanoparticles: An Antibiofilm Treatment

Start date: July 13, 2020
Phase: Phase 4
Study type: Interventional

The goal of this observational is study is to develop a protocol for root canal biofilms disinfection using a clinically approved and commercially available iron oxide nanoparticle formulation Ferumoxytol/H2O2 treatments. This protocol will be testing local single topical application of Ferumoxytol within the root canal system in patients going through routine root canal treatment, evaluate its potential as anti-biofilm treatment and compare it to the clinical gold standard disinfecting solution sodium hypochlorite (positive control) and saline (negative control).

NCT ID: NCT06002646 Completed - Clinical trials for Pulp Disease, Dental

Lasers as an Alternative to Formocresol and Sodium Hypochlorite Medicaments in Pulpotomy Techniques

Start date: January 4, 2023
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to evaluate the dental lasers as an alternative of chemical medicaments used in the pulpotomy procedures. The main question it aims to answer is: • Lasers pulpotomies are a viable alternative to the standard Formocresol and Sodium Hypochlorite medicaments. All participants groups (Formocresol, Sodium Hypochlorite, Diode and Er:Cr;YSGG lasers) for pulpotomy procedure will follow the same clinical protocol, except for the techniques that will be used for hemostasis of the pulpotomies which either will be achieved by Formocresol or Sodium Hypochlorite solutions or by Diode or Erbium lasers.

NCT ID: NCT05981352 Not yet recruiting - Clinical trials for Pulp Disease, Dental

Evaluation of Different Materials in Pulpotomy of Primary Molars

Start date: October 2023
Phase: N/A
Study type: Interventional

The aim of the current study is to evaluate and compare clinical and radiographic success and antibacterial effect of Hyaluronic Acid and Amniotic membrane pulpotomy in primary molars in comparison with MTA pulpotomy (Randomized Clinical Trial and In Vitro Study).