Clinical Trials Logo

Clinical Trial Summary

Pulmonary infections remain the leading causes of morbidity and mortality among patients worldwide. Pathogen identification is crucial yet difficult for the majority of the cases. Metagenomic Next-generation Sequencing provides a potential technology for rapid and untargeted pathogen detection for pulmonary infection. The study is designed observationally to investigate if mNGS is superior to traditional paradigm of serial tests in the aspect of diagnostic performance. Patients whose primary diagnosis is pulmonary infetion and bronchoalveolar lavage fluid can be obtained will be enrolled. Both mNGS and traditional paradigm of serial tests wil be performed.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03798925
Study type Observational
Source Sir Run Run Shaw Hospital
Contact
Status Recruiting
Phase
Start date August 19, 2018
Completion date February 2019

See also
  Status Clinical Trial Phase
Recruiting NCT03687177 - Visual Cue as Prevention of Pulmonary Infection Under Mechanical Ventilation N/A
Completed NCT03995030 - Massively Parallel Sequencing to Identify Microbiological Organisms in Bronchoalveolar Lavage Fluid
Recruiting NCT05552872 - Study on Diagnosis Value of mNGS Technology Among Diabetic Patients With Pulmonary Infections
Not yet recruiting NCT04583046 - Effects of Iloprost on Pulmonary Oxygenation in Obese Patients During One-lung Ventilation N/A
Recruiting NCT04624490 - Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease Phase 1
Recruiting NCT05505487 - Construction and Effect Evaluation of Integrated Care Model for Pulmonary Infection in Stroke Patients With Tracheotomy N/A
Terminated NCT04348513 - Triiodothyronine for the Treatment of Critically Ill Patients With COVID-19 Infection Phase 2
Completed NCT03438383 - Bi-PAP vs Sham Bi-PAP on Pulmonary Function in Morbidly Obese Patients After Bariatric Surgery N/A
Completed NCT03933878 - Rapid Detection of Airway Pathogens for Lung Transplantation
Completed NCT05844215 - MMP-9, TIMP-9 in Lung Imaging and Functional of COVID-19
Completed NCT02779595 - Change of Regional Ventilation During Spontaneous Breathing After Lung Surgery N/A
Recruiting NCT06368388 - Bacteriophage Therapy for Difficult-to-treat Infections: the Implementation of a Multidisciplinary Phage Task Force
Recruiting NCT04457609 - Administration of Allogenic UC-MSCs as Adjuvant Therapy for Critically-Ill COVID-19 Patients Phase 1
Completed NCT01525121 - Expiratory Rib Cage Compression in Mechanically Ventilated Patients N/A
Active, not recruiting NCT03617393 - Study on Appropriate Technology of Standardized Diagnosis and Treatment for Diabetic Patients With Pulmonary Infections
Terminated NCT04422691 - Ultrasonography in Norwegian Emergency Department Patients With Suspected Covid-19 Infection
Completed NCT05226403 - COVID-19 : Pulmonary Ultrasound in Primary Care
Completed NCT04553315 - the Effect of Chest Expansion Exercises on Pleural Effusion N/A
Recruiting NCT06282835 - Eravacycline Combination Therapy for MRAB
Completed NCT02419196 - Perioperative Change of Regional Ventilation During Spontaneous Breathing N/A