Upfront Combination Pulmonary Arterial Hypertension Therapy

Status Recruiting

Clinical Trial Summary

To evaluate the safety and efficacy of first-line combination therapy using riociguat with ambrisentan in patients with Pulmonary Arterial Hypertension (PAH).

Clinical Trial Description

This is a prospective, multi-center, open-label, exploratory study with patients followed for a period of one year. The treatment duration period in this study begins at the initiation of ambrisentan plus riociguat and will continue for 12 months. Patients will come to clinic for a visit at month 4 and 12. Assessments will include Right Heart Catheterization, 6 Minute walk test, cardiac MRI, questionnaires and nt-Pro-BNP. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03809156
Study type	Interventional
Source	University of Calgary
Contact	Naushad Hirani, MD
Phone	403 943 4759
Status	Recruiting
Phase	Phase 4
Start date	April 26, 2016
Completion date	January 31, 2021

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