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NCT06031311 Clinical Trial

Pulmonaryhypertension in Copd at Different Levels of Smoking

Pulmonary Hypertension Clinical Trial

Official title:
Clinical Characteristics and Predictors of Pulmonary Hypertension in COPD at Different Levels of Smoking

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT06031311
Other study ID # Pulmonaryhypertension in copd
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date October 1, 2023
Est. completion date December 1, 2024

Study information
Verified date September 2023
Source Assiut University
Contact Shrouk Mohamed Salah, Resident physician
Phone 01150637673
Email Shrouksalah806@gmail.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

To identify Predictors of pulmonary hypertension in COPD patients and its relation to different levels of smoking

Description:

COPD is a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea, cough, expectoration and/or exacerbations) due to abnormalities of the airways (bronchitis, bronchiolitis) and/or alveoli (emphysema) that cause persistent, often progressive, airflow obstruction.It is also the most common cause of deaths in patients with chronic respiratory disease, the fatality rate in USA is 0.41%.Pulmonary Hypertension is the most common serious complication in COPD patients ; which occurs in up to 30% of patients and increases the mortality rate.Smoking is the leading cause of chronic obstructive pulmonary disease (COPD) Smoking is also a trigger for COPD flare-ups.Smoking damages the air sacs, airways, and the lining of your lungs. Injured lungs have trouble moving enough air in and out, so it's hard to breathe

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 138
Est. completion date December 1, 2024
Est. primary completion date October 1, 2024
Accepts healthy volunteers
Gender All
Age group 18 Years to 100 Years
Eligibility Inclusion Criteria: - 1.All patients admitted to chest department or presented to our outpatient clinic with clinical and functional diagnosis of COPD among both sexes will be included 2.Age >18 years Old Exclusion Criteria: - 1.Patients under 18 years old. 2.pregnant patients. 3.patients with history hypertension or valvular diseases 4.Cardiomyopathic patient 5.Patients with concomitant obstructive sleep apnea 6.Patients with collagen vascular disease 7.Patients with thrombo-embolic disease 8. Patients with any chronic chest disease other than COPD

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Echocardiography and HRCT
Echocardiography:is non invasive and easily accessible tool in the diagnosis of any patient with suspected PH.HRCT: is a non-invasive and easily accessible tool to detect pulmonary hypertension in COPD patients.

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Assiut University

Outcome
Type Measure Description Time frame Safety issue
Primary Predictors of pulmonary hypertension in COPD patients Predict pulmonary hypertension in COPD patients 1 year
Secondary Relationship between different levels of smoking and predictors of degree of pulmonary hypertension Levels of smoking (mild.moderate.sever.non smoker) and it's relation to pulmonary hypertension in COPD patients 1 year
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