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Trial to Evaluate Parenteral Treprostinil and Riociguat on Right Ventriculo-vascular Coupling and Morphology in Those With Advanced PAH

Pulmonary Arterial Hypertension Clinical Trial

Official title:
A Prospective Trial to Evaluate Up-front Parenteral Treprostinil and Riociguat on Right Ventriculo-vascular Coupling and Morphology in Patients With Advanced Pulmonary Arterial Hypertension (IIR-3810)

Clinical Trial Summary

The purpose of this study is to determine if there is a greater effect to patients with advanced pulmonary arterial hypertension (PAH) by using a combination of two drugs, Treprostinil and Riociquat versus Treprostinil alone

Clinical Trial Description

The purpose of this study is to evaluate the combined effect of parenteral treprostinil (TRE) and riociguat (RIO) versus parenteral TRE alone on right ventricular (RV)-pulmonary artery (PA) interaction (RVPA coupling) and global RV function in patients with advanced pulmonary arterial hypertension (PAH). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04062565
Study type Interventional
Source University of Arizona
Contact Valerie Boss, MS
Phone 520-626-8305
Email vbloss@email.arizona.edu
Status Recruiting
Phase Phase 3
Start date March 25, 2019
Completion date December 2021
View Details
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