PTSD Clinical Trial
Official title:
Effect of D-cycloserine on Treatment of PTSD in Youth
The purpose of this study is to show whether D-cycloserine in combination with cognitive behavioral therapy (CBT) is more effective than CBT alone to reduce symptoms of posttraumatic stress disorder (PTSD) in 7-12 year old children.
Status | Active, not recruiting |
Enrollment | 56 |
Est. completion date | June 2012 |
Est. primary completion date | June 2012 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 7 Years to 12 Years |
Eligibility |
Inclusion Criteria: - Certain number of PTSD symptoms plus functional impairment - Must be able to swallow pills Exclusion Criteria: - Serious kidney or liver disease - Epilepsy - Bipolar - Psychosis |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
United States | Tulane University Health Sciences Center, 1440 Canal St. | New Orleans | Louisiana |
Lead Sponsor | Collaborator |
---|---|
Tulane University School of Medicine | National Institute of Mental Health (NIMH) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Number of PTSD symptoms | Symptoms established from diagnostic interview. | After 12 therapy sessions. | No |
Secondary | Attentional bias | Measured as reaction time on laptop computer by individuals response to pressing key to an asterisk appearing on the computer screen. | After 12 therapy sessions. | No |
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