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Investigations of Amygdala Function Using Neurophysiological Recording and Stimulation

PTSD Clinical Trial

Official title:
Investigations of Amygdala Function Using Neurophysiological Recording and Stimulation

Clinical Trial Summary

This study aims to specifically examine the in vivo electrophysiology and effects of direct stimulation of the human amygdala during conditioned and evoked fear. Investigators will also examine amygdala electrophysiology and the effects of stimulation during tasks to examine the effects of reward on fear memory. This study will recruit subjects with a history of temporal lobe epilepsy (TLE) who have undergone neurosurgical implantation with FDA-approved, NeuroPace RNS devices for treatment of seizures. These patients provide a unique cohort with (Responsive Neurostimulation) RNS devices capable of both recording and stimulating the amygdala during performance of fear-based, behavioral tasks.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03958903
Study type Interventional
Source Stanford University
Contact
Status Completed
Phase N/A
Start date April 24, 2019
Completion date March 13, 2020
View Details
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