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Psoriasis clinical trials

View clinical trials related to Psoriasis.

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NCT ID: NCT03122353 Completed - Scalp Psoriasis Clinical Trials

BE Study of Calcipotriene Hydrate and Betamethasone Dipropionate Topical Suspension in the Treatment of Scalp Psoriasis

Start date: April 11, 2017
Phase: Phase 1
Study type: Interventional

This study will be conducted to evaluate the therapeutic bioequivalence of a TEST formulation of calcipotriene hydrate and betamethasone dipropionate topical suspension 0.005%/0.064% to the RLD.

NCT ID: NCT03099083 Completed - Psoriasis Clinical Trials

Real-World Outcome of Psoriasis Subjects in Korea on Adalimumab

RAPSODI
Start date: March 31, 2017
Phase:
Study type: Observational

The objective of this non-interventional, observational study is to assess the effect of adalimumab on health-related quality of life in participants with Psoriasis in Korea.

NCT ID: NCT03097003 Completed - Psoriasis Clinical Trials

A Study of the Real-life Management of Psoriasis Patients Treated With Otezla® (Apremilast) in Belgium

OTELO
Start date: April 6, 2017
Phase:
Study type: Observational

OTELO is a national (Belgium), multicentre, prospective, non-interventional, post-marketing study. The study will include a representative sample of approximately 250 patients with moderate-to-severe plaque psoriasis for whom the treating dermatologist has decided to begin apremilast treatment in accordance with the local label and reimbursement criteria. Patients may be enrolled into the study up to 4 weeks after commencing the study treatment. As this study is non-interventional, drug dosing and treatment duration will be at the sole discretion of the treating dermatologist, in accordance with the local label and daily clinical practice.

NCT ID: NCT03090100 Completed - Psoriasis Clinical Trials

A Study to Evaluate the Comparative Efficacy of CNTO 1959 (Guselkumab) and Secukinumab for the Treatment of Moderate to Severe Plaque-type Psoriasis

ECLIPSE
Start date: April 27, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of guselkumab compared with secukinumab for the treatment of participants with moderate to severe plaque-type psoriasis.

NCT ID: NCT03084146 Completed - Psoriasis Clinical Trials

The Role of Food Sensitivity in Psoriasis

Start date: August 28, 2017
Phase: N/A
Study type: Interventional

Psoriasis is a common chronic skin disorder that affects over 4 million people. There is no cure for psoriasis and treatment is directed at controlling patients' symptoms. The purpose of this study is to determine whether psoriasis patients are more likely to have food sensitivities than those patients without psoriasis. We will also determine if eliminating certain foods from the diet results in a change in psoriasis symptoms.

NCT ID: NCT03082729 Completed - Clinical trials for Cardiovascular Diseases

Vascular Inflammation in Psoriasis - Apremilast

VIP-A
Start date: April 24, 2017
Phase: Phase 4
Study type: Interventional

The purpose of the VIP-A study is to determine the effect of apremilast on aortic vascular inflammation, cardiometabolic biomarkers and body composition in patients with moderate-severe psoriasis.

NCT ID: NCT03080545 Completed - Psoriasis Clinical Trials

Enstilar in Combination With Biologic Agents

Start date: May 1, 2017
Phase: Phase 4
Study type: Interventional

Patients receiving biologic therapy with 5% or less body surface area will receive Enstilar topical foam for 16 weeks.

NCT ID: NCT03079973 Withdrawn - Nail Psoriasis Clinical Trials

Study to Evaluate the Efficacy and Safety of P-3073 Nail Solution in the Treatment of Mild to Moderate Psoriatic Fingernail/s

Start date: May 15, 2017
Phase: Phase 3
Study type: Interventional

The objective of this phase III study is to evaluate the efficacy, systemic safety and local tolerability of P-3073 (calcipotriene 0.005%) nail solution in patients with mild to moderate psoriatic fingernail/s.

NCT ID: NCT03074656 Completed - Clinical trials for Rheumatoid Arthritis

The Norwegian Drug Monitoring Study

NOR-DRUM
Start date: March 1, 2017
Phase: N/A
Study type: Interventional

Infliximab and other TNF-inhibitors have revolutionised the treatment of several immunological inflammatory diseases. Still, more than half of the patients either do not respond sufficiently to infliximab therapy or loose efficacy over time. The large individual variation in the serum drug concentrations on standard doses and the development of anti-drug antibodies are thought to be main reasons for these treatment failures. An individualised treatment strategy based on systematic assessments of serum drug concentrations, therapeutic drug monitoring, has been proposed as a clinical tool to optimise efficacy of infliximab treatment. Therapeutic drug monitoring seems reasonable both from a clinical and an economical point of view, but the effectiveness of this treatment strategy still remain to be shown. The NOR-DRUM study is planned as a national, randomised controlled multicentre trial in two parts aiming to assess the effectiveness of therapeutic drug monitoring in order to achieve remission in patients with immunological inflammatory diseases starting infliximab treatment (part A) and in order to maintain disease control in patients on maintenance infliximab treatment (part B). The results of the NOR-DRUM study will hopefully contribute to an implementation of a personalised medicine approach to treatment with infliximab and other biological drugs.

NCT ID: NCT03073213 Completed - Psoriasis Clinical Trials

A Study of Ixekizumab in Chinese Participants With Psoriasis Vulgaris

Start date: April 13, 2017
Phase: Phase 1
Study type: Interventional

The purpose of the study is to research how much ixekizumab enters the bloodstream and how long the body takes to get rid of the drug and the safety of ixekizumab and any side effects that might be associated with it. The study has two parts: A single-dose part and multiple-dose part. The single dose part of this study will last up to 24 weeks, including the screening period. The multiple dose part of this study will last up to 32 weeks including the screening period.