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Clinical Trial Summary

1. To elucidate the role of CTC detection in the evaluation of risk level in PCa patients, and establish a mathematic model for predicting the pathological status.

2. To explore the possible subtle change in CTC condition after radical prostatectomy.


Clinical Trial Description

1. Detect and evaluate the CTC status (a total of 3 times: 1 day before sugery, 3/12 months after surgery) for all of the PCa patients enrolled. Analyze the CTC result with PSA level, needle biopsy and radiological imaging information.

2. Analyze the difference in CTC amount/Epithelial-Mesenchymal ratio between patients in different D'Amico risk level(low/intermediate/high).

3. Establish a mathematic model based on the CTC results and pathological condition observed in operation (OC, organ confined; EPE, extraprostatic extension; SVI, seminal vesicle invasion; LNI, lymph node invasion), and compare this model with the latest version of Partin table.

4. Detect and compare the CTC and PSA level 3/12 months after surgery. Evaluate the radiological condition in 12 months after blood draw. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02940977
Study type Observational
Source Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Contact Jun Qi, MD.
Phone 021-20578080
Email jasonqi@sh163.net
Status Recruiting
Phase
Start date October 1, 2016
Completion date March 30, 2019

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