Clinical Trials Logo

Prostatic Hyperplasia clinical trials

View clinical trials related to Prostatic Hyperplasia.

Filter by:

NCT ID: NCT04757116 Recruiting - Clinical trials for Benign Prostatic Hyperplasia (BPH)

Post-Market Study to Assess iTind Safety in Comparison to UroLift

MT-08
Start date: September 26, 2022
Phase: N/A
Study type: Interventional

The study objective is to evaluate the safety of the iTind device comparied to UroLift.

NCT ID: NCT04726748 Recruiting - Clinical trials for Benign Prostatic Hyperplasia

Economic Evaluation of Prostatic Urethral Lift

ECOLIFT
Start date: April 8, 2021
Phase:
Study type: Observational

Prostatic urethral lift (Urolift) has been developed as a minimally invasive alternative to transurethral resection of the prostate with no need of general anaesthesia, less need of urinary catheter and less exposure to post-operative complication. Its efficacy and safety have been assessed by 2 clinical randomized trials with evidence of urinary symptom improvement remaining inferior to TURP but durable for 5 years. Urolift preserved overall quality of life better than TURP. Urolift has been recommended by the European Association of Urology guidelines and recognized by French authorities but cannot be financed by the hospital itself. Reimbursement of the implants by healthcare system is therefore needed for the distribution of Urolift in France. The additional cost of the implants could be compensated by a reduced length of hospital stay and a lower rate of post-operative complications inducing healthcare expenditures. This study aims to assess if Urolift could be a cost-effective therapeutic strategy compared to transurethral surgery with 2 phases design: a field study comparing patients treated with Urolift to those treated with TURP/laser during 1 year follow-up, and an additional study comparing healthcare consumptions during 3 years follow-up between each group using data of the French National Claims Database (SNDS database).

NCT ID: NCT04693507 Completed - Prostatic Adenoma Clinical Trials

Teverelix Evaluated in Advanced Prostate Cancer

TEACh
Start date: March 4, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the safety and efficacy of teverelix TFA in the treatment of advanced prostate cancer

NCT ID: NCT04681625 Completed - Overactive Bladder Clinical Trials

Evaluation of Silodosin and Pelvic Floor Muscle Training in Men With Benign Prostatic Hyperplasia and Overactive Bladder

SILODOSING
Start date: January 11, 2021
Phase: N/A
Study type: Interventional

This study will evaluate the efficacy of pelvic floor muscle training in men with benign prostatic hyperplasia and overactive bladder treated with Silodosin.

NCT ID: NCT04658056 Not yet recruiting - Clinical trials for Benign Prostatic Hyperplasia

UK Post-market Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue

Start date: January 2021
Phase:
Study type: Observational

A post-market, non-interventional, two-arm, long-term follow-up study of patients previously enrolled in the WATER Study (NCT02505919) - which was a prospective multi-centre randomized blinded study comparing Aquablation of the prostate with the AQUABEAM Robotic System with standard transurethral resection of the prostate (TURP) for the treatment of lower urinary tract symptoms (LUTS).

NCT ID: NCT04648176 Recruiting - Clinical trials for Lower Urinary Tract Symptoms

Application of MOSES Technology in BPH

Start date: March 6, 2020
Phase: N/A
Study type: Interventional

In this study the investigators intend to compare the surgical and functional results of two different modalities of the use of the Holmium laser in prostate enucleation.

NCT ID: NCT04627701 Recruiting - Clinical trials for Benign Prostatic Hyperplasia

Omega Study: Evaluation of the Safety and Efficacy of the Omega System for the Treatment of BPH

Start date: July 23, 2023
Phase: N/A
Study type: Interventional

The ProArc Medical Omega system is a prostatic reshaping device that is designed to treat Lower Urinary Tract Symptoms (LUTS) due to BPH. During the procedure an implant is delivered into the prostate tissue obstructing the urethra and restricting urine flow. The delivery system uses a static diathermy incision mechanism to make a circumferential incision in the tissue surrounding the prostatic urethra into which the Omega shaped permanent implant is placed. The implant expands the obstructed area, reducing the fluid obstruction through the prostatic urethra.

NCT ID: NCT04590534 Recruiting - Clinical trials for Prostatic Hyperplasia

Evaluation of the Effect of Garcinia in Combination With Chromium on the Clinical Outcomes of Patients With LUTS/BPH

BPH
Start date: August 1, 2020
Phase: Phase 2
Study type: Interventional

To evaluate efficacy and safety of garcinia extract + chromium combinations (Chromax) in symptomatic benign prostatic hypertrophy patients

NCT ID: NCT04588857 Recruiting - Clinical trials for Prostatic Hyperplasia

Efficacy of a Single Dose Dexamethasone in Reducing the Postembolization Syndrome in Men Undergoing Prostatic Artery Embolization for Benign Prostatic Hyperplasia

Start date: March 1, 2021
Phase: Phase 4
Study type: Interventional

Benign prostatic hyperplasia (BPH) is a frequent cause of lower urinary tract symptoms (LUTS) in men. One fourth of men older than 70 have moderate to severe LUTS that impair their quality of life (QOL). Prostatic artery embolization (PAE) is a new minimally invasive technique proven effective in reducing LUTS comparable to the mainstay treatment - the transurethral resection of the prostate (TURP). The most common side effect of PAE is a collection of inflammation-related symptoms known as the postembolization syndrome (PES). The symptoms include pelvic pain, fever, nausea, and transient worsening of LUTS (painful and difficult urination). PES is a self-limiting condition that is treated symptomatically with painkillers and antipyretics. However, PES can be so severe that the patients experience high fever, shivers, dysuria and urgency mimicking a septicemia from the urinary tract. It is a clinical challenge to avoid exposure to unnecessary antibiotics treatment in those situations. A subset of patients may need admission to the hospital for observation, especially in case of fever. Usually, PES resolves within a week after PAE. Steroids have been successfully used to reduce the incidence and severity of PES after a number of procedures in interventional radiology. The investigators postulate that steroids can have a similar effect in reducing PES after PAE. In this study, the efficacy of single high dose postprocedural dexamethasone (DEXA) administration in reducing PES after PAE will be evaluated, compared to placebo.

NCT ID: NCT04580628 Completed - Clinical trials for Prostate Hyperplasia

Thuflep/SOLEP : Initial Experience and Results of Prostate Laser Enucleation With Thulium-fiber Laser (TFL)

Start date: July 1, 2020
Phase:
Study type: Observational

Thuflep TLF: initial experience and results of prostate laser enucleation with fibrous thulium laser (TLF)