Prostate Cancer Risk in Firefighters

Prostatic Cancer Clinical Trial

Official title:

Prostate Cancer Risk in Firefighters: Its Association to Qualitative and Quantitative Indicators of Exposure

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT03893123
• Other study ID #: 2016/2282
• Status: Active, not recruiting
• Start date: January 1, 2018
• Est. completion date: December 2021

Study information

• Verified date: March 2020
• Source: Oslo University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Firefighters have been shown to be at increased risk for various types of cancer, including prostate cancer. This study will try to explore possible reasons for this increase in risk. A study group at the Cancer Registry of Norway is creating a cohort of Norwegian firemen employed from 1960 onwards. A job exposure matrix (JEM) is also being constructed, examining different types of exposure to potentially cancer-inducing agents and activities, and how these have changed historically. Examples include exposure to fire-smoke, shiftwork, diesel exhaust and regular health check-ups. By linking the cohort with data from the Cancer Registry of Norway and the JEM the investigators can examine which exposure assessments, if any, are related to an increased risk of prostate cancer.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 4500
• Est. completion date: December 2021
• Est. primary completion date: February 1, 2020
• Accepts healthy volunteers: No
• Gender: Male
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Work as firefighter as recorded by the participating fire stations

Exclusion Criteria:

• Any other occupation, including chimney sweepers

Related Conditions & MeSH terms

• Prostatic Cancer
• Prostatic Neoplasms

Intervention

Other:
• Observational study, prostate cancer is outcome of interest
Observational study

Locations

Country	Name	City	State
Norway	Cancer Registry of Norway	Oslo

Sponsors (10)

Lead Sponsor	Collaborator
Oslo University Hospital	Cancer Registry of Norway, Extrastiftelsen, Fagforbundet, Gjensidige Foundation, National Institute of Occupational Health, Norwegian Cancer Society, Norwegian Confederation of Trade Unions, Norwegian Firefighters Fight Cancer, Norwegian Labour Inspection Authority

Country where clinical trial is conducted

Norway, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Incidence of prostate cancer	As reported to the Cancer Registry of Norway	From January 1st 1960 until December 31st 2018