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Prostate Disease clinical trials

View clinical trials related to Prostate Disease.

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NCT ID: NCT03658408 Withdrawn - Prostate Disease Clinical Trials

4-aminopyridine Treatment for Nerve Injury From Radical Retro-Pubic Prostatectomy

Start date: October 3, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to see if the study drug 4-aminopyridine (4-AP) can help speed up the recovery of peripheral nerve injury after prostatectomy. 4-AP is a potassium channel blocker used to improve walking in multiple sclerosis patients. Investigators will measure the effect that 4-AP may have on the recovery of sexual function and urinary incontinence after prostatectomy.

NCT ID: NCT03597386 Withdrawn - Prostate Disease Clinical Trials

ConfirmMDx Assay in Multiparametric MRI (mpMRI) PIRADS Scored Lesions After a Negative MR/US Fusion Biopsy

Start date: January 23, 2019
Phase:
Study type: Observational

The purpose of this study is to see if the ConfirmMDx assay is useful in finding prostate cancer in patients who are at increased risk for prostate cancer based on elevated PSA and prostate lesion identified on mpMRI.

NCT ID: NCT03589196 Enrolling by invitation - Clinical trials for Prostatic Hyperplasia

Ejaculation Preserving Photoselective Vaporization Versus Plasma Kinetic Vaporization Versus Transurethral Resection Of The Prostate: A RCT

EPPROSTATECT
Start date: March 10, 2018
Phase: N/A
Study type: Interventional

To Evaluate and compare the outcome and coast of ejaculation sparing management of BPH using 3 different techniques: PVP, PKVP and TURP. Ejaculation sparing TURP group is considered the standard control group. Evaluation will be carried out through a prospective randomized powered trial

NCT ID: NCT03543189 Active, not recruiting - Prostate Cancer Clinical Trials

Combination of Nivolumab Immunotherapy With Radiation Therapy and Androgen Deprivation Therapy

Start date: October 3, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to test the safety, tolerability, and effectiveness of the investigational drug nivolumab (Opdivoâ„¢) in combination with high dose radiation. Investigators also want to see if these study drugs help to delay the progression of prostate cancer.

NCT ID: NCT03503643 Enrolling by invitation - Prostate Cancer Clinical Trials

Hemi-Gland Cryoablation for Prostate Cancer at UCLA

Start date: September 14, 2017
Phase:
Study type: Observational

This is a prospective data collection of men who are electing to undergo prostate hemi-gland cryoablation. The purpose of this observational research study is to investigate the localized treatment of prostate cancer using hemi-gland cryoablation. UCLA patients undergoing hemi-gland cryoablation are a unique cohort compared to prior research because all patients at UCLA have had a pre-treatment multi-parametric MRI and Ultrasound fusion targeted biopsy; they will be followed in a similar fashion. This results in more precise assessment of a target region of cancer for ablation which may, in turn, result in improved clinical outcomes.

NCT ID: NCT01307852 Completed - Prostate Disease Clinical Trials

In Vivo Dosimetry During Prostate Cancer Radiotherapy

Start date: November 2011
Phase: Phase 1
Study type: Interventional

The goal of this clinical research study is to learn if a rectal balloon with attached radiation detectors can be used to help researchers monitor the dose of external beam radiation that is delivered to the prostate during treatment. This may help researchers better understand the side effects of radiation therapy, such as rectal bleeding, and may lead to changes in treatment planning or treatment delivery.

NCT ID: NCT00756561 Completed - Healthy Clinical Trials

HOP-2A - Intratesticular Hormone Levels

HOP-2A
Start date: September 2008
Phase: N/A
Study type: Observational

The purpose of this investigational study is to find out what hormones are present in healthy male testicles using fine needle aspiration.

NCT ID: NCT00037141 Completed - Clinical trials for Benign Prostatic Hyperplasia

Safety/Tolerability Study of Alcohol Injection for Treatment of BPH (Enlarged Prostate)

Start date: March 2002
Phase: Phase 1/Phase 2
Study type: Interventional

Multi-center, prospective randomized dosing and safety research study. A maximum of 150 men will be enrolled in the study. Qualifying patients will receive one of three possible doses of the study drug. Symptoms will be evaluated before treatment, and then 1-week, 1-month, 3-months, and 6-months following treatment.