Evaluation of Four Treatment Modalities in Prostate Cancer With Low or "Early Intermediate" Risk — PREFERE  

Prostate Cancer Clinical Trial

Official title: Preference Based Randomized Trial for Evaluation of Four Treatment Modalities in Prostate Cancer With Low or "Early Intermediate" Risk

Status Terminated

Clinical Trial Summary

4arms preference based Study to compare four therapy options in prostate cancer with low or early intermediate risk

Clinical Trial Description

The study will compare four possible therapy options for treatment of newly diagnosed prostate cancer with low or "early intermediate" risk according to the patients preferences.

The Following hypotheses will be tested:

• Radiation is not relevantly worse compared to prostatectomy with regard to time to prostate cancer-related deaths

• Permanent seed implantation therapy not inferior to prostatectomy with regard to time to prostate cancer-related deaths.

• Active Surveillance does not lead to a significant decrease of time to prostate cancer-related deaths compared to prostatectomy.

That for patients with newly diagnosed prostate cancer will be randomized into one of the four treatment arms. Randomization may be limited to at least two of the four treatment arms if a patient refuses one or two of the four treatment arms according to his own preference. ;

Related Conditions & MeSH terms

• Prostate Cancer
• Prostatic Neoplasms

• NCT number: NCT01717677
• Study type: Interventional
• Source: Association of Urologic Oncology (AUO)
• Status: Terminated
• Phase: N/A
• Start date: October 2012
• Completion date: April 30, 2018