Prostate Cancer Clinical Trial
Official title:
Metformin With Standard Taxotere and Prednisone in the Treatment of Castration Resistant Prostate Cancer
This study is being conducted to determine the effectiveness of standard 3 weekly treatments
using docetaxel and prednisone with metformin in patients with castration-resistant
metastatic prostate cancer.
It is also being conducted to determine the levels of toxicity of metformin when added to
every 3 weekly docetaxel treatments in patients with endocrine resistent, metastatic
prostate cancer.
This is a single-arm, non-randomized Phase II trial of docetaxel given every 3 weeks with metformin twice daily and Prednisone twice daily. The study duration of this trial is open ended. The patient would take the metformin only for as long as they are treated with docetaxel. ;
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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